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Registro Completo |
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
27/01/2021 |
Data da última atualização: |
15/06/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
FRAUCHES, N. S.; MONTENEGRO, J.; AMARAL, T.; ABREU, J. P.; LAIBER, G.; JORGE JUNIOR; BORGUINI, R. G.; SANTIAGO, M. C. P. de A.; PACHECO, S.; NAKAJIMA, V. M.; GODOY, R. L. de O.; TEODORO, A. J. |
Afiliação: |
Nayara Simas Frauches, UNIRIO; Júlia Montenegro, UNIRIO; Thuane Amaral, UNIRIO; Joel Pimentel Abreu, UNIRIO; Gabriela Laiber, UNIRIO; Jorge Junior, UFRJ; RENATA GALHARDO BORGUINI, CTAA; MANUELA CRISTINA P DE A SANTIAGO, CTAA; SIDNEY PACHECO, CTAA; Vania Mayumi Nakajima, UFF; RONOEL LUIZ DE OLIVEIRA GODOY, CTAA; Anderson Junger Teodoro, UNIRIO. |
Título: |
Antiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Molecules, v. 26, n. 564 , 2021. p. 1-16. |
DOI: |
https://doi.org/10.3390/molecules26030564 |
Idioma: |
Inglês |
Conteúdo: |
There is a significant indication of the beneficial health effects of fruit rich diets. Fruitsof native plant species have noticeably different phytochemicals and bioactive effects. The aim ofthis work was to characterize and compare the constituents of jabuticaba (Myrciaria jaboticaba, MJ),jamun-berry (Syzygium cumini, SC), and malay-apple (Syzygium malaccense, SM) extracts and theirinfluence on antioxidant activityin vitroand antiproliferative effects on human colon adenocarci-noma cells. According to the results, dried peel powders (DP) have a high anthocyanin content,phenolic compounds, and antioxidant activity when compared to freeze dried extracts (FD).M.jaboticabadried peel powder extract had a higher total anthocyanin and phenolic compounds content(802.90±1.93 and 2152.92±43.95 mg/100 g, respectively). A reduction in cell viability of HT-29cells after treatment withM. jaboticabaextracts (DP-MJ and FD-MJ) was observed via MTT assay.Flow cytometry showed that the treatment with the anthocyanin-rich extracts from MJ, SC, and SMhad an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cellsin relation to the control group. The findings of this study highlight the potential of peel powdersfromMyrtaceaefruits as an important source of natural antioxidants and a protective effect againstcolon adenocarcinoma |
Palavras-Chave: |
Colon cancer; Jamun-berry; Malay-apple; Myrtaceae fruits. |
Thesagro: |
Jabuticaba. |
Thesaurus Nal: |
Bioactive compounds. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/220691/1/molecules-26-00564.pdf
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Marc: |
LEADER 02414naa a2200337 a 4500 001 2129588 005 2021-06-15 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3390/molecules26030564$2DOI 100 1 $aFRAUCHES, N. S. 245 $aAntiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family.$h[electronic resource] 260 $c2021 520 $aThere is a significant indication of the beneficial health effects of fruit rich diets. Fruitsof native plant species have noticeably different phytochemicals and bioactive effects. The aim ofthis work was to characterize and compare the constituents of jabuticaba (Myrciaria jaboticaba, MJ),jamun-berry (Syzygium cumini, SC), and malay-apple (Syzygium malaccense, SM) extracts and theirinfluence on antioxidant activityin vitroand antiproliferative effects on human colon adenocarci-noma cells. According to the results, dried peel powders (DP) have a high anthocyanin content,phenolic compounds, and antioxidant activity when compared to freeze dried extracts (FD).M.jaboticabadried peel powder extract had a higher total anthocyanin and phenolic compounds content(802.90±1.93 and 2152.92±43.95 mg/100 g, respectively). A reduction in cell viability of HT-29cells after treatment withM. jaboticabaextracts (DP-MJ and FD-MJ) was observed via MTT assay.Flow cytometry showed that the treatment with the anthocyanin-rich extracts from MJ, SC, and SMhad an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cellsin relation to the control group. The findings of this study highlight the potential of peel powdersfromMyrtaceaefruits as an important source of natural antioxidants and a protective effect againstcolon adenocarcinoma 650 $aBioactive compounds 650 $aJabuticaba 653 $aColon cancer 653 $aJamun-berry 653 $aMalay-apple 653 $aMyrtaceae fruits 700 1 $aMONTENEGRO, J. 700 1 $aAMARAL, T. 700 1 $aABREU, J. P. 700 1 $aLAIBER, G. 700 1 $aJORGE JUNIOR 700 1 $aBORGUINI, R. G. 700 1 $aSANTIAGO, M. C. P. de A. 700 1 $aPACHECO, S. 700 1 $aNAKAJIMA, V. M. 700 1 $aGODOY, R. L. de O. 700 1 $aTEODORO, A. J. 773 $tMolecules$gv. 26, n. 564 , 2021. p. 1-16.
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Registro original: |
Embrapa Agroindústria de Alimentos (CTAA) |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
09/04/2010 |
Data da última atualização: |
25/09/2019 |
Tipo da produção científica: |
Resumo em Anais de Congresso |
Autoria: |
ALBUQUERQUE, L. de F.; MORENO, A. M. B.; DUTRA, L. A.; PARENTE, H. N.; CARVALHO, F. C. de; ARAUJO FILHO, J. A. de. |
Afiliação: |
João Ambrósio de Araújo Filho, CNPC. |
Título: |
Composição percentual do litter em um sistema agrossilvipastoail no Nordeste brasileiro. |
Ano de publicação: |
2005 |
Fonte/Imprenta: |
In: ENCONTRO DE INICIAÇÃO CIENTÍFICA DA UVA, 7., 2005, Sobral. Anais... Sobral: Universidade Estadual Vale do Acaraú, 2005. p. 10. |
Idioma: |
Português |
Palavras-Chave: |
Brasil; Nordeste; Sistema agroflorestal. |
Thesagro: |
Caatinga; Nutriente; Solo. |
Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/49664/1/RAC-Composicao-percentual.pdf
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Marc: |
LEADER 00772nam a2200229 a 4500 001 1663656 005 2019-09-25 008 2005 bl uuuu u00u1 u #d 100 1 $aALBUQUERQUE, L. de F. 245 $aComposição percentual do litter em um sistema agrossilvipastoail no Nordeste brasileiro.$h[electronic resource] 260 $aIn: ENCONTRO DE INICIAÇÃO CIENTÍFICA DA UVA, 7., 2005, Sobral. Anais... Sobral: Universidade Estadual Vale do Acaraú, 2005. p. 10.$c2005 650 $aCaatinga 650 $aNutriente 650 $aSolo 653 $aBrasil 653 $aNordeste 653 $aSistema agroflorestal 700 1 $aMORENO, A. M. B. 700 1 $aDUTRA, L. A. 700 1 $aPARENTE, H. N. 700 1 $aCARVALHO, F. C. de 700 1 $aARAUJO FILHO, J. A. de
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