02414naa a2200337 a 450000100080000000500110000800800410001902400510006010000200011124501980013126000090032952013730033865000240171165000150173565300170175065300160176765300160178365300210179970000190182070000150183970000170185470000150187170000170188670000200190370000290192370000160195270000200196870000230198870000190201177300460203021295882021-06-15       2021    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.3390/molecules260305642DOI1 aFRAUCHES, N. S.  aAntiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family.h[electronic resource]  c2021  aThere is a significant indication of the beneficial health effects of fruit rich diets. Fruitsof native plant species have noticeably different phytochemicals and bioactive effects. The aim ofthis work was to characterize and compare the constituents of jabuticaba (Myrciaria jaboticaba, MJ),jamun-berry (Syzygium cumini, SC), and malay-apple (Syzygium malaccense, SM) extracts and theirinfluence on antioxidant activityin vitroand antiproliferative effects on human colon adenocarci-noma cells. According to the results, dried peel powders (DP) have a high anthocyanin content,phenolic compounds, and antioxidant activity when compared to freeze dried extracts (FD).M.jaboticabadried peel powder extract had a higher total anthocyanin and phenolic compounds content(802.90±1.93 and 2152.92±43.95 mg/100 g, respectively). A reduction in cell viability of HT-29cells after treatment withM. jaboticabaextracts (DP-MJ and FD-MJ) was observed via MTT assay.Flow cytometry showed that the treatment with the anthocyanin-rich extracts from MJ, SC, and SMhad an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cellsin relation to the control group. The findings of this study highlight the potential of peel powdersfromMyrtaceaefruits as an important source of natural antioxidants and a protective effect againstcolon adenocarcinoma  aBioactive compounds  aJabuticaba  aColon cancer  aJamun-berry  aMalay-apple  aMyrtaceae fruits1 aMONTENEGRO, J.1 aAMARAL, T.1 aABREU, J. P.1 aLAIBER, G.1 aJORGE JUNIOR1 aBORGUINI, R. G.1 aSANTIAGO, M. C. P. de A.1 aPACHECO, S.1 aNAKAJIMA, V. M.1 aGODOY, R. L. de O.1 aTEODORO, A. J.  tMoleculesgv. 26, n. 564 , 2021. p. 1-16.