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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
20/02/2019 |
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Data da última atualização: |
08/03/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BEHURA, S. K.; TIZIOTO, P. C.; KIM, J.; GRUPIONI, N. V.; SEABURY, C. M.; SCHNABEL, R. D.; GERSHWIN, L. J.; VAN EEnenNAAM, A. L.; TOAF-FROSENSTEIN, R.; NEIBERGS, H. L.; REGITANO, L. C. de A.; TAYLOR, J. F. |
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Afiliação: |
Susanta K. Behura, University of Missouri; Polyana C. Tizioto, University of Missouri; JaeWoo Kim, University of Missouri; Natalia V. Grupioni, UNESP; Christopher M. Seabury, Texas A&M University; Robert D. Schnabel, University of Missouri; Laurel J. Gershwin, University of California; Alison L. Van Eenennaam, University of California; Rachel Toaff-Rosenstein, University of California; Holly L. Neibergs, Washington State University; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; Jeremy F. Taylor, University of Missouri. |
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Título: |
Tissue tropism in host transcriptional response to members of the bovine respiratory disease complex. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Scientific Reports, v.7, n. 17938, p. 1-15, 2017. |
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DOI: |
10.1038/s41598-017-18205-0 |
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Idioma: |
Inglês |
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Conteúdo: |
Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens. We examined the global changes in mRNA abundance in healthy lung and lung lesions and in the lymphoid tissues bronchial lymph node, retropharyngeal lymph node, nasopharyngeal lymph node and pharyngeal tonsil collected at the peak of clinical disease from beef cattle experimentally challenged with either bovine respiratory syncytial virus, infectious bovine rhinotracheitis, bovine viral diarrhea virus, Mannheimia haemolytica or Mycoplasma bovis. We identified signatures of tissue-specific transcriptional responses indicative of tropism in the coordination of host?s immune tissue responses to infection by viral or bacterial infections. Furthermore, our study shows that this tissue tropism in host transcriptional response to BRD pathogens results in the activation of different networks of response genes. The differential crosstalk among genes expressed in lymphoid tissues was predicted to be orchestrated by specific immune genes that act as ?key players? within expression networks. The results of this study serve as a basis for the development of innovative therapeutic strategies and for the selection of cattle with enhanced resistance to BRD. |
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Palavras-Chave: |
Bovinos de corte; BRD; MRNA. |
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Thesagro: |
Doença Respiratória; Gado de Corte. |
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Thesaurus Nal: |
Beef cattle; Bovine respiratory disease. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/193126/1/11-Tissue-Tropism-in-Host-Transcriptional-Response-to-Members-of-the-Bovine-Respiratory-Disease-Complex.pdf
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Marc: |
LEADER 02380naa a2200349 a 4500
001 2106292
005 2019-03-08
008 2017 bl uuuu u00u1 u #d
024 7 $a10.1038/s41598-017-18205-0$2DOI
100 1 $aBEHURA, S. K.
245 $aTissue tropism in host transcriptional response to members of the bovine respiratory disease complex.$h[electronic resource]
260 $c2017
520 $aBovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens. We examined the global changes in mRNA abundance in healthy lung and lung lesions and in the lymphoid tissues bronchial lymph node, retropharyngeal lymph node, nasopharyngeal lymph node and pharyngeal tonsil collected at the peak of clinical disease from beef cattle experimentally challenged with either bovine respiratory syncytial virus, infectious bovine rhinotracheitis, bovine viral diarrhea virus, Mannheimia haemolytica or Mycoplasma bovis. We identified signatures of tissue-specific transcriptional responses indicative of tropism in the coordination of host?s immune tissue responses to infection by viral or bacterial infections. Furthermore, our study shows that this tissue tropism in host transcriptional response to BRD pathogens results in the activation of different networks of response genes. The differential crosstalk among genes expressed in lymphoid tissues was predicted to be orchestrated by specific immune genes that act as ?key players? within expression networks. The results of this study serve as a basis for the development of innovative therapeutic strategies and for the selection of cattle with enhanced resistance to BRD.
650 $aBeef cattle
650 $aBovine respiratory disease
650 $aDoença Respiratória
650 $aGado de Corte
653 $aBovinos de corte
653 $aBRD
653 $aMRNA
700 1 $aTIZIOTO, P. C.
700 1 $aKIM, J.
700 1 $aGRUPIONI, N. V.
700 1 $aSEABURY, C. M.
700 1 $aSCHNABEL, R. D.
700 1 $aGERSHWIN, L. J.
700 1 $aVAN EEnenNAAM, A. L.
700 1 $aTOAF-FROSENSTEIN, R.
700 1 $aNEIBERGS, H. L.
700 1 $aREGITANO, L. C. de A.
700 1 $aTAYLOR, J. F.
773 $tScientific Reports$gv.7, n. 17938, p. 1-15, 2017.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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Registro Completo
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Biblioteca(s): |
Embrapa Instrumentação. |
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Data corrente: |
27/09/2022 |
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Data da última atualização: |
27/09/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
GIROTO, A. S.; VALLE, S. F. do; GUIMARÃES, G. G. F.; WUYTS, N.; OHREM, B.; JABLONOWSKI, N. D.; RIBEIRO, C.; MATTOSO, L. H. C. |
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Afiliação: |
CAUE RIBEIRO DE OLIVEIRA, CNPDIA; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA. |
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Título: |
Zinc loading in urea-formaldehyde nanocomposites increases nitrogen and zinc micronutrient fertilization efficiencies in poor sand substrate. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Science of the Total Environment, v. 841, 156688, 2022. |
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Páginas: |
1 - 10 |
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ISSN: |
0048-9697 |
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DOI: |
http://dx.doi.org/10.1016/j.scitotenv.2022.156688 |
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Idioma: |
Inglês |
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Conteúdo: |
Agricultural output needs significant increases to feed the growing population. Fertilizers are essential for plant production systems, with nitrogen (N) being the most limiting nutrient for plant growth. It is commonly supplied to crops as urea. Still, due to volatilization, up to 50 % of the total N application is lost. Slow or controlled release fertilizers are being developed to reduce these losses. The co-application of zinc (Zn) as a micronutrient can increase N absorption. Thus, we hypothesize that the controlled delivery of both nutrients (N and Zn) in an integrated system can improve uptake efficiency. Here we demonstrate an optimized fertilizer nanocomposite based on urea:urea-formaldehyde matrix loaded with ZnSO4 or ZnO. This nanocomposite effectively stimulates maize development, with consequent adequate N uptake, in an extreme condition ? a very nutrient-poor sand substrate. Our results indicate that the Zn co-application is beneficial for plant development. However, there were advantages for ZnO due to its high Zn content. We discuss that the dispersion favors the Zn delivery as the nanoparticulated oxide in the matrix. Concerning maize development, we found that root morphology is altered in the presence of the fertilizer nanocomposite. Increased root length and surface area may improve soil nutrient uptake, potentially accompanied by increased root exudation of essential compounds for N release from the composite structure. |
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Palavras-Chave: |
Controlled-release; Fertilizer; Nitrogen losses; Urea-formaldehyde. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1146881/1/P-Zinc-loading-in-urea-formaldehyde-nanocomposites-increases-nitrogen-and.pdf
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Marc: |
LEADER 02372naa a2200289 a 4500
001 2146881
005 2022-09-27
008 2022 bl uuuu u00u1 u #d
022 $a0048-9697
024 7 $ahttp://dx.doi.org/10.1016/j.scitotenv.2022.156688$2DOI
100 1 $aGIROTO, A. S.
245 $aZinc loading in urea-formaldehyde nanocomposites increases nitrogen and zinc micronutrient fertilization efficiencies in poor sand substrate.$h[electronic resource]
260 $c2022
300 $a1 - 10
520 $aAgricultural output needs significant increases to feed the growing population. Fertilizers are essential for plant production systems, with nitrogen (N) being the most limiting nutrient for plant growth. It is commonly supplied to crops as urea. Still, due to volatilization, up to 50 % of the total N application is lost. Slow or controlled release fertilizers are being developed to reduce these losses. The co-application of zinc (Zn) as a micronutrient can increase N absorption. Thus, we hypothesize that the controlled delivery of both nutrients (N and Zn) in an integrated system can improve uptake efficiency. Here we demonstrate an optimized fertilizer nanocomposite based on urea:urea-formaldehyde matrix loaded with ZnSO4 or ZnO. This nanocomposite effectively stimulates maize development, with consequent adequate N uptake, in an extreme condition ? a very nutrient-poor sand substrate. Our results indicate that the Zn co-application is beneficial for plant development. However, there were advantages for ZnO due to its high Zn content. We discuss that the dispersion favors the Zn delivery as the nanoparticulated oxide in the matrix. Concerning maize development, we found that root morphology is altered in the presence of the fertilizer nanocomposite. Increased root length and surface area may improve soil nutrient uptake, potentially accompanied by increased root exudation of essential compounds for N release from the composite structure.
653 $aControlled-release
653 $aFertilizer
653 $aNitrogen losses
653 $aUrea-formaldehyde
700 1 $aVALLE, S. F. do
700 1 $aGUIMARÃES, G. G. F.
700 1 $aWUYTS, N.
700 1 $aOHREM, B.
700 1 $aJABLONOWSKI, N. D.
700 1 $aRIBEIRO, C.
700 1 $aMATTOSO, L. H. C.
773 $tScience of the Total Environment$gv. 841, 156688, 2022.
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Embrapa Instrumentação (CNPDIA) |
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