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4. | | ANDREOTTI, R.; GIACHETTO, P. F. Phylogenetic of phylogeographic relations of Rhipicephalus microplus ( Acari: ixodidae) in Brazil. In: AMERICAN ASSOCIATION OF VETERINARY PARASITOLOGISTS ANNUAL MEETING, 60.; LIVESTOCK INSECT WORKERS CON-FERENCE, 59.; INTERNATIONAL SYMPOSIUM ON ECTOPARASITES OF PETS, 13.,2015, Boston, MA. Parasitic Evolution Scientific Revolu-tion: Proceedings... Boston, MA: American Association of Veterinary Parasitologists, 2015. Resumo 146. 1 p. Biblioteca(s): Embrapa Gado de Corte. |
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Registros recuperados : 126 | |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Agricultura Digital. Para informações adicionais entre em contato com cnptia.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Agricultura Digital. |
Data corrente: |
23/06/2009 |
Data da última atualização: |
15/01/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
CASTRO, A. de; FRONZA, C. F.; GIACHETTO, P. F.; ALVES, D. |
Afiliação: |
ALEXANDRE DE CASTRO, CNPTIA; CARLOS FREDERICO FRONZA, UNIFESP; POLIANA FERNANDA GIACHETTO, CNPTIA; DOMINGOS ALVES, UNIFESP, USP. |
Título: |
Influence of antigenic mutations in time evolution of the immune memory - a dynamic modeling. |
Ano de publicação: |
2009 |
Fonte/Imprenta: |
Lecture Notes in Computer Science, v. 5676, p. 133-142. |
DOI: |
10.1007/978-3-642-03223-3_12 |
Idioma: |
Inglês |
Notas: |
Proceedings of the 4th Brazilian Symposium on Bioinformatics, 2009, held in Porto Alegre, Brazil, in July 2009. |
Conteúdo: |
In this paper, we study the behavior of immune memory against antigenic mutation. Using a dynamic model proposed in previous studies, we have performed simulations of several inoculations, where in each virtual sample the viral population undergoes mutations. Our results suggest that the sustainability of the immunizations is dependent on viral variability and that the memory lifetimes are not random, what contradicts what was suggested by recent works. We show that what may cause an apparent random behavior of the immune memoory is the antigenic variability. |
Palavras-Chave: |
Anticorpos; B-cell evolution; Evolução de célula-B; Immune memory; Memória imunológica; Modelagem; Modelo dinâmico; Mutação antigênica; Mutação viral; Viral mutation. |
Thesagro: |
Imunização; Simulação. |
Thesaurus NAL: |
Models. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
Marc: |
LEADER 01635naa a2200337 a 4500 001 1082751 005 2020-01-15 008 2009 bl uuuu u00u1 u #d 024 7 $a10.1007/978-3-642-03223-3_12$2DOI 100 1 $aCASTRO, A. de 245 $aInfluence of antigenic mutations in time evolution of the immune memory - a dynamic modeling.$h[electronic resource] 260 $c2009 500 $aProceedings of the 4th Brazilian Symposium on Bioinformatics, 2009, held in Porto Alegre, Brazil, in July 2009. 520 $aIn this paper, we study the behavior of immune memory against antigenic mutation. Using a dynamic model proposed in previous studies, we have performed simulations of several inoculations, where in each virtual sample the viral population undergoes mutations. Our results suggest that the sustainability of the immunizations is dependent on viral variability and that the memory lifetimes are not random, what contradicts what was suggested by recent works. We show that what may cause an apparent random behavior of the immune memoory is the antigenic variability. 650 $aModels 650 $aImunização 650 $aSimulação 653 $aAnticorpos 653 $aB-cell evolution 653 $aEvolução de célula-B 653 $aImmune memory 653 $aMemória imunológica 653 $aModelagem 653 $aModelo dinâmico 653 $aMutação antigênica 653 $aMutação viral 653 $aViral mutation 700 1 $aFRONZA, C. F. 700 1 $aGIACHETTO, P. F. 700 1 $aALVES, D. 773 $tLecture Notes in Computer Science$gv. 5676, p. 133-142.
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Embrapa Agricultura Digital (CNPTIA) |
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