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Registro Completo |
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Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
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Data corrente: |
27/01/2021 |
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Data da última atualização: |
15/06/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
FRAUCHES, N. S.; MONTENEGRO, J.; AMARAL, T.; ABREU, J. P.; LAIBER, G.; JORGE JUNIOR; BORGUINI, R. G.; SANTIAGO, M. C. P. de A.; PACHECO, S.; NAKAJIMA, V. M.; GODOY, R. L. de O.; TEODORO, A. J. |
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Afiliação: |
Nayara Simas Frauches, UNIRIO; Júlia Montenegro, UNIRIO; Thuane Amaral, UNIRIO; Joel Pimentel Abreu, UNIRIO; Gabriela Laiber, UNIRIO; Jorge Junior, UFRJ; RENATA GALHARDO BORGUINI, CTAA; MANUELA CRISTINA P DE A SANTIAGO, CTAA; SIDNEY PACHECO, CTAA; Vania Mayumi Nakajima, UFF; RONOEL LUIZ DE OLIVEIRA GODOY, CTAA; Anderson Junger Teodoro, UNIRIO. |
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Título: |
Antiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Molecules, v. 26, n. 564 , 2021. p. 1-16. |
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DOI: |
https://doi.org/10.3390/molecules26030564 |
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Idioma: |
Inglês |
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Conteúdo: |
There is a significant indication of the beneficial health effects of fruit rich diets. Fruitsof native plant species have noticeably different phytochemicals and bioactive effects. The aim ofthis work was to characterize and compare the constituents of jabuticaba (Myrciaria jaboticaba, MJ),jamun-berry (Syzygium cumini, SC), and malay-apple (Syzygium malaccense, SM) extracts and theirinfluence on antioxidant activityin vitroand antiproliferative effects on human colon adenocarci-noma cells. According to the results, dried peel powders (DP) have a high anthocyanin content,phenolic compounds, and antioxidant activity when compared to freeze dried extracts (FD).M.jaboticabadried peel powder extract had a higher total anthocyanin and phenolic compounds content(802.90±1.93 and 2152.92±43.95 mg/100 g, respectively). A reduction in cell viability of HT-29cells after treatment withM. jaboticabaextracts (DP-MJ and FD-MJ) was observed via MTT assay.Flow cytometry showed that the treatment with the anthocyanin-rich extracts from MJ, SC, and SMhad an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cellsin relation to the control group. The findings of this study highlight the potential of peel powdersfromMyrtaceaefruits as an important source of natural antioxidants and a protective effect againstcolon adenocarcinoma |
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Palavras-Chave: |
Colon cancer; Jamun-berry; Malay-apple; Myrtaceae fruits. |
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Thesagro: |
Jabuticaba. |
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Thesaurus Nal: |
Bioactive compounds. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/220691/1/molecules-26-00564.pdf
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Marc: |
LEADER 02414naa a2200337 a 4500
001 2129588
005 2021-06-15
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.3390/molecules26030564$2DOI
100 1 $aFRAUCHES, N. S.
245 $aAntiproliferative Activity on Human Colon Adenocarcinoma Cells and In Vitro Antioxidant Effect of Anthocyanin-Rich Extracts from Peels of Species of the Myrtaceae Family.$h[electronic resource]
260 $c2021
520 $aThere is a significant indication of the beneficial health effects of fruit rich diets. Fruitsof native plant species have noticeably different phytochemicals and bioactive effects. The aim ofthis work was to characterize and compare the constituents of jabuticaba (Myrciaria jaboticaba, MJ),jamun-berry (Syzygium cumini, SC), and malay-apple (Syzygium malaccense, SM) extracts and theirinfluence on antioxidant activityin vitroand antiproliferative effects on human colon adenocarci-noma cells. According to the results, dried peel powders (DP) have a high anthocyanin content,phenolic compounds, and antioxidant activity when compared to freeze dried extracts (FD).M.jaboticabadried peel powder extract had a higher total anthocyanin and phenolic compounds content(802.90±1.93 and 2152.92±43.95 mg/100 g, respectively). A reduction in cell viability of HT-29cells after treatment withM. jaboticabaextracts (DP-MJ and FD-MJ) was observed via MTT assay.Flow cytometry showed that the treatment with the anthocyanin-rich extracts from MJ, SC, and SMhad an inhibitory impact on cell development due to G2/M arrest and caused a rise in apoptotic cellsin relation to the control group. The findings of this study highlight the potential of peel powdersfromMyrtaceaefruits as an important source of natural antioxidants and a protective effect againstcolon adenocarcinoma
650 $aBioactive compounds
650 $aJabuticaba
653 $aColon cancer
653 $aJamun-berry
653 $aMalay-apple
653 $aMyrtaceae fruits
700 1 $aMONTENEGRO, J.
700 1 $aAMARAL, T.
700 1 $aABREU, J. P.
700 1 $aLAIBER, G.
700 1 $aJORGE JUNIOR
700 1 $aBORGUINI, R. G.
700 1 $aSANTIAGO, M. C. P. de A.
700 1 $aPACHECO, S.
700 1 $aNAKAJIMA, V. M.
700 1 $aGODOY, R. L. de O.
700 1 $aTEODORO, A. J.
773 $tMolecules$gv. 26, n. 564 , 2021. p. 1-16.
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Registro original: |
Embrapa Agroindústria de Alimentos (CTAA) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Hortaliças. Para informações adicionais entre em contato com cnph.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Hortaliças. |
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Data corrente: |
25/02/2005 |
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Data da última atualização: |
28/05/2018 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
ÁVILA, A. C. de; INOUE-NAGATA, A. K.; COSTA, H.; BOITEUX, L. S.; NEVES, L. O. de Q.; PRATES, R. S.; BERTINI, L. A. |
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Afiliação: |
ANTONIO CARLOS DE ÁVILA, CNPH; ALICE KAZUKO INOUE NAGATA, CNPH; HELCIO COSTA, INCAPER-ES; LEONARDO SILVA BOITEUX, CNPH; LUIZ O. de Q. NEVES, MINISTÉRIO DA AGRICULTURA PECUÁRIA E ABASTECIMENTO; RICARDO S. PRATES, MINISTÉRIO DA AGRICULTURA PECUÁRIA E ABASTECIMENTO; LEOPOLDO A. BERTINI, MINISTÉRIO DA AGRICULTURA PECUÁRIA E ABASTECIMENTO. |
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Título: |
Viruses occurrence in tomato and sweetpepper in the highland region of the State of Espirito Santo. |
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Ano de publicação: |
2004 |
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Fonte/Imprenta: |
Fitopatologia Brasileira, Brasília, v. 29, p. S114, ago. 2004. |
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Idioma: |
Inglês |
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Notas: |
Suplemento. Resumo 315. Trabalho apresentado no 37º Congresso Brasileiro de Fitopatologia, 2004. |
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Palavras-Chave: |
Análise sorológica; Brasil; Espírito Santo. |
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Thesagro: |
Capsicum Annuum; Doença; Epidemiologia; Hospedeiro; Levantamento; Lycopersicon Esculentum; Pimentão; Sintoma; Tomate; Vírus. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01053nam a2200337 a 4500
001 1777770
005 2018-05-28
008 2004 bl uuuu u00u1 u #d
100 1 $aÁVILA, A. C. de
245 $aViruses occurrence in tomato and sweetpepper in the highland region of the State of Espirito Santo.$h[electronic resource]
260 $aFitopatologia Brasileira, Brasília, v. 29, p. S114, ago. 2004.$c2004
500 $aSuplemento. Resumo 315. Trabalho apresentado no 37º Congresso Brasileiro de Fitopatologia, 2004.
650 $aCapsicum Annuum
650 $aDoença
650 $aEpidemiologia
650 $aHospedeiro
650 $aLevantamento
650 $aLycopersicon Esculentum
650 $aPimentão
650 $aSintoma
650 $aTomate
650 $aVírus
653 $aAnálise sorológica
653 $aBrasil
653 $aEspírito Santo
700 1 $aINOUE-NAGATA, A. K.
700 1 $aCOSTA, H.
700 1 $aBOITEUX, L. S.
700 1 $aNEVES, L. O. de Q.
700 1 $aPRATES, R. S.
700 1 $aBERTINI, L. A.
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