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![](/consulta/web/img/deny.png) | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite; Embrapa Instrumentação. |
Data corrente: |
06/09/2023 |
Data da última atualização: |
13/09/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
ZANETTE, R. de S. S.; FAYER, L.; VASCONCELLOS, R.; OLIVEIRA, L. F. C. de; MARANDUBA, C. M. da C.; ALVARENGA, E. L. F. C. de; MARTINS, M. A.; BRANDAO, H. de M.; MUNK, M. |
Afiliação: |
RAFAELLA DE SOUZA SALOMÃO ZANETTE, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; LEONARA FAYER, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; REBECCA VASCONCELLOS, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; LUIZ FERNANDO CAPPA DE OLIVEIRA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; CARLOS MAGNO DA COSTA MARANDUBA, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; ERIKA LORENA FONSECA COSTA DE ALVARENGA, UNIVERSIDADE FEDERAL DE SÃO JOÃO DEL-REY; MARIA ALICE MARTINS, CNPDIA; HUMBERTO DE MELLO BRANDAO, CNPGL; MICHELE MUNK, UNIVERSIDADE FEDERAL DE JUIZ DE FORA. |
Título: |
Cytocompatible and osteoinductive cotton cellulose nanofiber/chitosan nanobiocomposite scaffold for bone tissue engineering. |
Ano de publicação: |
2023 |
Fonte/Imprenta: |
Biomedical Materials, v. 18, 055016, 2023. |
DOI: |
http://doi.org/10.1088/1748-605X/aceac8 |
Idioma: |
Inglês |
Conteúdo: |
Natural polymeric nanobiocomposites hold promise in repairing damaged bone tissue in tissue engineering. These materials create an extracellular matrix (ECM)-like microenvironment that induces stem cell differentiation. In this study, we investigated a new cytocompatible nanobiocomposite made from cotton cellulose nanofibers (CNFs) combined with chitosan polymer to induce osteogenic stem cell differentiation. First, we characterized the chemical composition, nanotopography, swelling properties, and mechanical properties of the cotton CNF/chitosan nanobiocomposite scaffold. Then, we examined the biological characteristics of the nanocomposites to evaluate their cytocompatibility and osteogenic differentiation potential using human mesenchymal stem cells derived from exfoliated deciduous teeth. The results showed that the nanobiocomposite exhibited favorable cytocompatibility and promoted osteogenic differentiation of cells without the need for chemical inducers, as demonstrated by the increase in alkaline phosphatase activity and ECM mineralization. Therefore, the cotton CNF/chitosan nanobiocomposite scaffold holds great promise for bone tissue engineering applications. |
Palavras-Chave: |
Biomedical nanomaterials; Human mesenchymal; Nanofibra; Tecido ósseo. |
Thesagro: |
Algodão; Célula; Celulose. |
Thesaurus Nal: |
Cell differentiation; Nanomaterials; Stem cells. |
Categoria do assunto: |
G Melhoramento Genético |
Marc: |
LEADER 02235naa a2200349 a 4500 001 2156507 005 2023-09-13 008 2023 bl uuuu u00u1 u #d 024 7 $ahttp://doi.org/10.1088/1748-605X/aceac8$2DOI 100 1 $aZANETTE, R. de S. S. 245 $aCytocompatible and osteoinductive cotton cellulose nanofiber/chitosan nanobiocomposite scaffold for bone tissue engineering.$h[electronic resource] 260 $c2023 520 $aNatural polymeric nanobiocomposites hold promise in repairing damaged bone tissue in tissue engineering. These materials create an extracellular matrix (ECM)-like microenvironment that induces stem cell differentiation. In this study, we investigated a new cytocompatible nanobiocomposite made from cotton cellulose nanofibers (CNFs) combined with chitosan polymer to induce osteogenic stem cell differentiation. First, we characterized the chemical composition, nanotopography, swelling properties, and mechanical properties of the cotton CNF/chitosan nanobiocomposite scaffold. Then, we examined the biological characteristics of the nanocomposites to evaluate their cytocompatibility and osteogenic differentiation potential using human mesenchymal stem cells derived from exfoliated deciduous teeth. The results showed that the nanobiocomposite exhibited favorable cytocompatibility and promoted osteogenic differentiation of cells without the need for chemical inducers, as demonstrated by the increase in alkaline phosphatase activity and ECM mineralization. Therefore, the cotton CNF/chitosan nanobiocomposite scaffold holds great promise for bone tissue engineering applications. 650 $aCell differentiation 650 $aNanomaterials 650 $aStem cells 650 $aAlgodão 650 $aCélula 650 $aCelulose 653 $aBiomedical nanomaterials 653 $aHuman mesenchymal 653 $aNanofibra 653 $aTecido ósseo 700 1 $aFAYER, L. 700 1 $aVASCONCELLOS, R. 700 1 $aOLIVEIRA, L. F. C. de 700 1 $aMARANDUBA, C. M. da C. 700 1 $aALVARENGA, E. L. F. C. de 700 1 $aMARTINS, M. A. 700 1 $aBRANDAO, H. de M. 700 1 $aMUNK, M. 773 $tBiomedical Materials$gv. 18, 055016, 2023.
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Registro original: |
Embrapa Instrumentação (CNPDIA) |
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![](/consulta/web/img/deny.png) | Acesso ao texto completo restrito à biblioteca da Embrapa Clima Temperado. Para informações adicionais entre em contato com cpact.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Clima Temperado. |
Data corrente: |
07/05/2019 |
Data da última atualização: |
31/05/2019 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
CHIOMENTO, J. L. T.; STRÜRMER, S. L.; CARRENHO, R.; COSTA, R. C. da; SCHEFFER-BASSO, S. M.; ANTUNES, L. E. C.; NIENOWA, A. A.; CALVETE, E. O. |
Afiliação: |
José Luís Trevizan Chiomento; Sidney Luiz Stürmer; Rosilaine Carrenho; Rosiani Castoldi da Costa; Simone Meredith Scheffer-Basso; LUIS EDUARDO CORREA ANTUNES, CPACT; Alexandre Augusto Nienow; Eunice Oliveira Calvete. |
Título: |
Composition of arbuscular mycorrhizal fungi communities signals generalist species in soils cultivated with strawberry. |
Ano de publicação: |
2019 |
Fonte/Imprenta: |
Scientia Horticulturae, v. 253, p. 286-294, 2019. |
Idioma: |
Inglês |
Palavras-Chave: |
Agricultural ecosystems; Diversity; Fragaria X ananassaduch Duch; Natural ecosystems. |
Thesaurus NAL: |
Rhizosphere. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00806naa a2200253 a 4500 001 2108828 005 2019-05-31 008 2019 bl uuuu u00u1 u #d 100 1 $aCHIOMENTO, J. L. T. 245 $aComposition of arbuscular mycorrhizal fungi communities signals generalist species in soils cultivated with strawberry.$h[electronic resource] 260 $c2019 650 $aRhizosphere 653 $aAgricultural ecosystems 653 $aDiversity 653 $aFragaria X ananassaduch Duch 653 $aNatural ecosystems 700 1 $aSTRÜRMER, S. L. 700 1 $aCARRENHO, R. 700 1 $aCOSTA, R. C. da 700 1 $aSCHEFFER-BASSO, S. M. 700 1 $aANTUNES, L. E. C. 700 1 $aNIENOWA, A. A. 700 1 $aCALVETE, E. O. 773 $tScientia Horticulturae$gv. 253, p. 286-294, 2019.
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