Registro Completo |
Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
Data corrente: |
14/12/1999 |
Data da última atualização: |
13/07/2023 |
Autoria: |
MARSHALL III, W. F.; TELFORD III, S. R.; RYS, P. N.; RUTLEDGE, B. J.; MATHIESEN, D.; MALAWISTA, S. E.; SPIELMAN, A.; PERSING, D. H. |
Título: |
Detection of Borrelia burgdorferi DNA museum specimens of Peromyscus leucopus. |
Ano de publicação: |
1994 |
Fonte/Imprenta: |
The Journal of Infections Diseases, v. 170, n. 4, p. 1027-1032, Oct. 1994. |
DOI: |
10.1093/infdis/170.4.1027. |
Idioma: |
Inglês |
Conteúdo: |
Abstract: To determine whether Borrelia burgdorferi was enzootic within the United States at the beginning of the 20th century, ear skin samples taken from museum specimens of the white-footed mouse (Peromyscus leucopus) were examined for evidence of spirochetal DNA. In total, 280 samples from mice collected between 1870 and 1919 were analyzed by a nested polymerase chain reaction protocol. Of these, 2 specimens from the vicinity of Dennis, Massachusetts, during 1894 were reproducibly positive for B. burgdorferi OspA sequences. The remaining 278, representing both currently endemic and nonendemic sites, were negative for spirochetal DNA. These studies suggest that the agent of Lyme disease was present in a suitable reservoir host in the United States before the turn of the century and provide evidence against a hypothesis of recent introduction of this zoonotic agent to North America. |
Palavras-Chave: |
Antigens surface; Bacterial Outer Membrane Proteins; Deteccao; DNA Viral; Museums; OspA protein; Skin. |
Thesagro: |
DNA; Vetor. |
Thesaurus Nal: |
Bacterial vaccines; Biosynthesis; Borrelia burgdorferi group; Epidemiology; Lipoproteins; Lyme disease; Microbiology. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02040naa a2200409 a 4500 001 1524056 005 2023-07-13 008 1994 bl uuuu u00u1 u #d 024 7 $a10.1093/infdis/170.4.1027.$2DOI 100 1 $aMARSHALL III, W. F. 245 $aDetection of Borrelia burgdorferi DNA museum specimens of Peromyscus leucopus.$h[electronic resource] 260 $c1994 520 $aAbstract: To determine whether Borrelia burgdorferi was enzootic within the United States at the beginning of the 20th century, ear skin samples taken from museum specimens of the white-footed mouse (Peromyscus leucopus) were examined for evidence of spirochetal DNA. In total, 280 samples from mice collected between 1870 and 1919 were analyzed by a nested polymerase chain reaction protocol. Of these, 2 specimens from the vicinity of Dennis, Massachusetts, during 1894 were reproducibly positive for B. burgdorferi OspA sequences. The remaining 278, representing both currently endemic and nonendemic sites, were negative for spirochetal DNA. These studies suggest that the agent of Lyme disease was present in a suitable reservoir host in the United States before the turn of the century and provide evidence against a hypothesis of recent introduction of this zoonotic agent to North America. 650 $aBacterial vaccines 650 $aBiosynthesis 650 $aBorrelia burgdorferi group 650 $aEpidemiology 650 $aLipoproteins 650 $aLyme disease 650 $aMicrobiology 650 $aDNA 650 $aVetor 653 $aAntigens surface 653 $aBacterial Outer Membrane Proteins 653 $aDeteccao 653 $aDNA Viral 653 $aMuseums 653 $aOspA protein 653 $aSkin 700 1 $aTELFORD III, S. R. 700 1 $aRYS, P. N. 700 1 $aRUTLEDGE, B. J. 700 1 $aMATHIESEN, D. 700 1 $aMALAWISTA, S. E. 700 1 $aSPIELMAN, A. 700 1 $aPERSING, D. H. 773 $tThe Journal of Infections Diseases$gv. 170, n. 4, p. 1027-1032, Oct. 1994.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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