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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
11/12/2000 |
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Data da última atualização: |
11/08/2023 |
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Autoria: |
CRASS, B. A.; BERGDOLL, M. S. |
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Título: |
Toxin involvement in toxic shock syndrome. |
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Ano de publicação: |
1986 |
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Fonte/Imprenta: |
The Journal of Infectious Diseases, v. 153, n. 5, p. 918-926, May, 1986. |
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DOI: |
10.1093/infdis/153.5.918 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Cultures for Staphylococcus and sera from 434 individuals with confirmed or probable toxic shock syndrome (TSS) were studied. Three hundred forty-eight (91.6%) of the staphylococcal isolates produced TSS toxin-1 (TSST-1) alone or in combination with one or more staphylococcal enterotoxins. Isolates producing both staphylococcal enterotoxin C and TSST-1 had a higher association with non menstrual and fatal cases than did any other toxin combination. The sera of 284 patients with TSS were tested for antibodies to TSST-1, and 234 (82.4%) had no detectable levelof antibody compared with 80 (77.7%) of 103 healthy controls having antibody levels of ?1:800. The sera from patients with TSS also had lower levels of antibody to staphylococcal enterotoxins A, B, and C than did the controls, a result indicating that these subjects may have an immunodeficiency that inhibits the production and/or maintenance of antibodies to the staphylococcal enterotoxins and TSST-1. |
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Palavras-Chave: |
Middle Aged; Virulencia. |
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Thesagro: |
Patogenicidade; Staphylococcus Aureus. |
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Thesaurus Nal: |
Bacterial toxins; Biosynthesis; Enterotoxins; Humans; Immunology; Septic shock. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01710naa a2200265 a 4500
001 1524188
005 2023-08-11
008 1986 bl uuuu u00u1 u #d
024 7 $a10.1093/infdis/153.5.918$2DOI
100 1 $aCRASS, B. A.
245 $aToxin involvement in toxic shock syndrome.$h[electronic resource]
260 $c1986
520 $aAbstract: Cultures for Staphylococcus and sera from 434 individuals with confirmed or probable toxic shock syndrome (TSS) were studied. Three hundred forty-eight (91.6%) of the staphylococcal isolates produced TSS toxin-1 (TSST-1) alone or in combination with one or more staphylococcal enterotoxins. Isolates producing both staphylococcal enterotoxin C and TSST-1 had a higher association with non menstrual and fatal cases than did any other toxin combination. The sera of 284 patients with TSS were tested for antibodies to TSST-1, and 234 (82.4%) had no detectable levelof antibody compared with 80 (77.7%) of 103 healthy controls having antibody levels of ?1:800. The sera from patients with TSS also had lower levels of antibody to staphylococcal enterotoxins A, B, and C than did the controls, a result indicating that these subjects may have an immunodeficiency that inhibits the production and/or maintenance of antibodies to the staphylococcal enterotoxins and TSST-1.
650 $aBacterial toxins
650 $aBiosynthesis
650 $aEnterotoxins
650 $aHumans
650 $aImmunology
650 $aSeptic shock
650 $aPatogenicidade
650 $aStaphylococcus Aureus
653 $aMiddle Aged
653 $aVirulencia
700 1 $aBERGDOLL, M. S.
773 $tThe Journal of Infectious Diseases$gv. 153, n. 5, p. 918-926, May, 1986.
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