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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
14/08/2025 |
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Autoria: |
MILLER, B. G.; MOORE, N. W. |
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Título: |
Effects of progesterone and oestradiol on RNA and protein metabolism in the genital tract and on survival of embryos in the ovariectomized ewe. |
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Ano de publicação: |
1976 |
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Fonte/Imprenta: |
Australian Journal Biology Science, v. 29, n. 5/6, p. 565-573, Dec. 1976. |
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DOI: |
10.1071/bi9760565 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: The hormonal regulation of metabolism in the genital tract and the development of embryos during early pregnancy in the ewe have been examined. Ovariectomized ewes received injections of maintenance progesterone, oestrous oestradiol and priming progesterone according to schedules designed to simulate endogenous ovarian secretion during early pregnancy, around the time of oestrus and during the luteal phase of the oestrous cycle immediately preceding oestrus. The survival and development of embryos was dependent upon the dose of maintenaince progesterone and the duration of treatment at the time of transfer, but changes in progesterone dose did not change endometrial protein or RNA metabolism on particular days. Both priming progesterone and oestrous oestradiol were required for normal embryo development. Priming progesterone and oestrous oestradiol each increased endometrial RNA/DNA ratios during early pregnancy. There were no interactions between priming progesterone and oestrous oestradiol, their effects being simply additive. Neither maintenance nor priming progesterone had any effect on protein and RNA metabolism in the oviduct. It is suggested that in the intact ewe oestrogen secreted at oestrus and progesterone secreted prior to oestrus play important roles in the establishment of a uterine environment suitable for the subsequent normal development of embryos. |
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Palavras-Chave: |
Drug effects; Ovary; Protein Biosynthesis. |
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Thesagro: |
Estradiol; Fisiologia; Ovino; Reprodução. |
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Thesaurus Nal: |
Animal physiology; Castration; Endometrium; Fallopian tubes; Metabolism; Pharmacology; Pregnancy; Progesterone; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02375naa a2200337 a 4500
001 1521367
005 2025-08-14
008 1976 bl uuuu u00u1 u #d
024 7 $a10.1071/bi9760565$2DOI
100 1 $aMILLER, B. G.
245 $aEffects of progesterone and oestradiol on RNA and protein metabolism in the genital tract and on survival of embryos in the ovariectomized ewe.$h[electronic resource]
260 $c1976
520 $aAbstract: The hormonal regulation of metabolism in the genital tract and the development of embryos during early pregnancy in the ewe have been examined. Ovariectomized ewes received injections of maintenance progesterone, oestrous oestradiol and priming progesterone according to schedules designed to simulate endogenous ovarian secretion during early pregnancy, around the time of oestrus and during the luteal phase of the oestrous cycle immediately preceding oestrus. The survival and development of embryos was dependent upon the dose of maintenaince progesterone and the duration of treatment at the time of transfer, but changes in progesterone dose did not change endometrial protein or RNA metabolism on particular days. Both priming progesterone and oestrous oestradiol were required for normal embryo development. Priming progesterone and oestrous oestradiol each increased endometrial RNA/DNA ratios during early pregnancy. There were no interactions between priming progesterone and oestrous oestradiol, their effects being simply additive. Neither maintenance nor priming progesterone had any effect on protein and RNA metabolism in the oviduct. It is suggested that in the intact ewe oestrogen secreted at oestrus and progesterone secreted prior to oestrus play important roles in the establishment of a uterine environment suitable for the subsequent normal development of embryos.
650 $aAnimal physiology
650 $aCastration
650 $aEndometrium
650 $aFallopian tubes
650 $aMetabolism
650 $aPharmacology
650 $aPregnancy
650 $aProgesterone
650 $aSheep
650 $aEstradiol
650 $aFisiologia
650 $aOvino
650 $aReprodução
653 $aDrug effects
653 $aOvary
653 $aProtein Biosynthesis
700 1 $aMOORE, N. W.
773 $tAustralian Journal Biology Science$gv. 29, n. 5/6, p. 565-573, Dec. 1976.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
