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Registro Completo |
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Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
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Data corrente: |
27/05/2021 |
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Data da última atualização: |
28/09/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
THEODORO, J. M. V.; MARTINEZ, O. D. M.; GRANCIERI, M.; TOLEDO, R. C. L.; BINOTI, M. L.; MARTINS, A. M. D.; CARVALHO, C. W. P. de; LISBOA, P. C.; MARTINO, H. S. |
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Afiliação: |
JAQUELINE MACIEL VIEIRA THEODORO, UFV; OSCAR DAVID MEDINA MARTINEZ, UFV; MARIANA GRANCIERI, UFV; RENATA CELI LOPES TOLEDO, UFV; MIRELLA LIMA BINOTI, UFV; AMANDA M. DIAS MARTINS, UFRRJ; CARLOS WANDERLEI PILER DE CARVALHO, CTAA; PATRÍCIA CRISTINA LISBOA, Universidade Estadual do Rio de Janeiro; HÉRCIA STAMPINI DUARTE MARTINO, UFV. |
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Título: |
Germinated millet flour (Pennisetum Glaucum (L.) R. BR.) improves adipogenesis and glucose metabolism and maintains thyroid function in vivo. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Food & Function, v. 12, p. 6083-6090, 2021. |
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DOI: |
https://doi.org/10.1039/D0FO03388J |
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Idioma: |
Inglês |
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Conteúdo: |
This study investigated the effects of germinated millet flour on adipogenesis, insulin resistance, glucose tolerance and thyroid function in Wistar rats fed with a high-fat high-fructose diet (HFHF). The experiment was divided into two phases. Phase 1: control group, which received AIN-93M diet (n = 10) and HFHF group (n = 20), which received a diet rich in saturated fat (31%) and fructose (20%), for eight weeks. Phase 2: intervention: the control group maintained the AIN-93M diet (n = 10) and the HFHF group was divided into two groups: the HFHF (n = 10) and the germinated millet group (n = 10), for 10 weeks. The germinated millet flour maintained (p>0, 05) the plasma levels of thyroid hormones, increased (p<0.05) the protein kinase B (AKT) mRNA expression and the phospho-AKT1 protein concentration, the phosphofructokinase (PFK) mRNA and activated protein kinase (AMPK) mRNA expression, and the brown adipose tissue and reduced (p<0.05) the glucose triglyceride index (TyG), glucose, insulin and hypercorticosteronemia, compared to the HFHF group. These effects contributed to reduce the gluconeogenesis, hyperinsulinemia and adiposity. Thus, germinated millet flour is a good alternative for modulating the adipogenesis and glucose metabolism, without interfering with the thyroid hormones, in rats with an insulin resistance condition with a high-fat high-fructose diet. |
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Thesaurus Nal: |
Food technology. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02176naa a2200241 a 4500
001 2132068
005 2021-09-28
008 2021 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1039/D0FO03388J$2DOI
100 1 $aTHEODORO, J. M. V.
245 $aGerminated millet flour (Pennisetum Glaucum (L.) R. BR.) improves adipogenesis and glucose metabolism and maintains thyroid function in vivo.$h[electronic resource]
260 $c2021
520 $aThis study investigated the effects of germinated millet flour on adipogenesis, insulin resistance, glucose tolerance and thyroid function in Wistar rats fed with a high-fat high-fructose diet (HFHF). The experiment was divided into two phases. Phase 1: control group, which received AIN-93M diet (n = 10) and HFHF group (n = 20), which received a diet rich in saturated fat (31%) and fructose (20%), for eight weeks. Phase 2: intervention: the control group maintained the AIN-93M diet (n = 10) and the HFHF group was divided into two groups: the HFHF (n = 10) and the germinated millet group (n = 10), for 10 weeks. The germinated millet flour maintained (p>0, 05) the plasma levels of thyroid hormones, increased (p<0.05) the protein kinase B (AKT) mRNA expression and the phospho-AKT1 protein concentration, the phosphofructokinase (PFK) mRNA and activated protein kinase (AMPK) mRNA expression, and the brown adipose tissue and reduced (p<0.05) the glucose triglyceride index (TyG), glucose, insulin and hypercorticosteronemia, compared to the HFHF group. These effects contributed to reduce the gluconeogenesis, hyperinsulinemia and adiposity. Thus, germinated millet flour is a good alternative for modulating the adipogenesis and glucose metabolism, without interfering with the thyroid hormones, in rats with an insulin resistance condition with a high-fat high-fructose diet.
650 $aFood technology
700 1 $aMARTINEZ, O. D. M.
700 1 $aGRANCIERI, M.
700 1 $aTOLEDO, R. C. L.
700 1 $aBINOTI, M. L.
700 1 $aMARTINS, A. M. D.
700 1 $aCARVALHO, C. W. P. de
700 1 $aLISBOA, P. C.
700 1 $aMARTINO, H. S.
773 $tFood & Function$gv. 12, p. 6083-6090, 2021.
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Embrapa Agroindústria de Alimentos (CTAA) |
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| 2. |  | GILES, A. L.; FREITAS, M. G.; ESPADA, A. L. V.; CONSTANTINO, P.; FRANCISCO, B. S.; RODRIGUES, S. B.; SAMPAIO, A. B.; FREITAS, I. F. de; BUENO, G. C. S.; LACERDA, R. C. A.; EDSON JÚNIOR, R.; SILVIUS, K.; VIEIRA, D. L. M. Brazil’s science–policy effort to monitor native vegetation restoration. Ambio, 2026. On-line first.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
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