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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Instrumentação; Embrapa Suínos e Aves. |
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Data corrente: |
05/10/2020 |
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Data da última atualização: |
05/10/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
COLNAGO, L. A.; TREVISOL, I. M.; VOSS RECH, D.; FORATO, L. A.; MITRE, C. I. N.; LEITE, J. P. G.; GIGLIOTI, R.; OKINO, C. H. |
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Afiliação: |
LUIZ ALBERTO COLNAGO, CNPDIA; IARA MARIA TREVISOL, CNPSA; LUCIMARA APARECIDA FORATO, CNPDIA; CINTIA HIROMI OKINO, CPPSE. |
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Título: |
Simple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
International Journal of Environmental Research and Public Health, v. 17, a. 6456, 2020. |
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Páginas: |
1 - 9 |
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DOI: |
10.3390/ijerph17186456 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal
among populations with lower socioeconomic status. Direct contact with contaminated surfaces has
been among the virus sources, as it remains infective up to days. Several disinfectants have been
shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be
scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare,
low-cost and effcient antiviral films, made with a widely available dishwashing detergent, which can
be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer
periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to
test the antivirus effcacy of the proposed films. Polystyrene petri dishes were covered with a thin
layer of detergent formula. After drying, the films were exposed to different virus doses for 10 min
and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification
in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50),
which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent
alternative to minimize the spread of COVID-19. |
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Palavras-Chave: |
Antiviral; Coronavirus; COVID-19; Detergent; Film; Sanitization; SARS-CoV-2; Virucide. |
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Thesagro: |
Aviário; Virologia. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02311naa a2200349 a 4500
001 2125283
005 2020-10-05
008 2020 bl uuuu u00u1 u #d
024 7 $a10.3390/ijerph17186456$2DOI
100 1 $aCOLNAGO, L. A.
245 $aSimple, low-cost and long-lasting film for virus inactivation using avian coronavirus model as challenge.$h[electronic resource]
260 $c2020
300 $a1 - 9
520 $aAbstract: The COVID-19 infection, caused by SARS-CoV-2, is inequitably distributed and more lethal among populations with lower socioeconomic status. Direct contact with contaminated surfaces has been among the virus sources, as it remains infective up to days. Several disinfectants have been shown to inactivate SARS-CoV-2, but they rapidly evaporate, are flammable or toxic and may be scarce or inexistent for vulnerable populations. Therefore, we are proposing simple, easy to prepare, low-cost and effcient antiviral films, made with a widely available dishwashing detergent, which can be spread on hands and inanimate surfaces and is expected to maintain virucidal activity for longer periods than the current sanitizers. Avian coronavirus (ACoV) was used as model of the challenge to test the antivirus effcacy of the proposed films. Polystyrene petri dishes were covered with a thin layer of detergent formula. After drying, the films were exposed to different virus doses for 10 min and virus infectivity was determined using embryonated chicken eggs, and RNA virus quantification in allantoic fluids by RT-qPCR. The films inactivated the ACoV (ranging from 103.7 to 106.7 EID50), which is chemically and morphologically similar to SARS-CoV-2, and may constitute an excellent alternative to minimize the spread of COVID-19.
650 $aAviário
650 $aVirologia
653 $aAntiviral
653 $aCoronavirus
653 $aCOVID-19
653 $aDetergent
653 $aFilm
653 $aSanitization
653 $aSARS-CoV-2
653 $aVirucide
700 1 $aTREVISOL, I. M.
700 1 $aVOSS RECH, D.
700 1 $aFORATO, L. A.
700 1 $aMITRE, C. I. N.
700 1 $aLEITE, J. P. G.
700 1 $aGIGLIOTI, R.
700 1 $aOKINO, C. H.
773 $tInternational Journal of Environmental Research and Public Health$gv. 17, a. 6456, 2020.
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