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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
12/12/2012 |
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Data da última atualização: |
24/03/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LAPORT, M. S.; MARINHO, P. R.; SANTOS, O. C. DA S.; ALMEIDA, P. DE; ROMANOS, M. T. V.; MURICY, G.; BRITO, M. A. V. P. e; GIAMBIAGI-DE-MARVAL, M. |
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Afiliação: |
MARINELLA SILVA LAPORTE, UFRJ; PALLOMA RODRIGUES MARINHO, UFRJ; OLINDA CABRAL DA SILVA SANTOS, UFRJ; PAULA DE ALMEIDA, UFRJ; MARIA TERESA VILLELA ROMANOS, UFRJ; GUILHERME MURICY, UFRJ; MARIA APARECIDA V PAIVA E BRITO, CNPGL; MARCIA GIAMBIAGI-DE-MARVAL, UFRJ. |
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Título: |
Antimicrobial activity of marine sponges against coagulase-negative staphylococci isolated from bovine mastitis. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Veterinary Microbiology, v. 155, p. 362-368, 2012. |
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Idioma: |
Inglês |
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Conteúdo: |
Bovine mastitis remains worldwide a major challenge for the dairy industry despite the widespread implementation of control strategies. The increasing number of coagulasenegative staphylococci (CNS) causing mastitis and of bacteria resistant to conventional antibiotics has become a serious problem in recent years. Marine sponges are a rich source of bioactive compounds, and many species can be useful for the development of new antimicrobial drugs. In the present study, 49 CNS strains were isolated from bovine mastitis cases from 21 different dairy herds kept at farms in Southeast Brazil. Strains were analyzed for antimicrobial susceptibility and mecA gene detection. Fifty-nine percent of the CNS strains were resistant to at least one of the drugs tested and 12.2% were classified as multiresistant. Three strains carried the mecA gene, confering resistance to the betalactamic antibiotics. In addition, the CNS strains were submitted to in vitro screening for antimicrobial activities of extracts from marine sponges. Extracts from the sponge species Cinachyrella sp., Haliclona sp. and Petromica citrina showed antibacterial activity against 61% of the CNS strains, including strains resistant to conventional antibiotics. Extracts from P. citrina showed the largest spectrum of inhibitory activity. The aqueous extract inhibited 51% of the CNS strains and presented a bactericidal effect over susceptible and multiresistant-bacteria at a minimal inhibitory concentration of 1.024 mg/ml. This study shows the potential of marine sponges as new sources of antibiotics and disinfectants for the control of CNS involved in bovine mastitis. MenosBovine mastitis remains worldwide a major challenge for the dairy industry despite the widespread implementation of control strategies. The increasing number of coagulasenegative staphylococci (CNS) causing mastitis and of bacteria resistant to conventional antibiotics has become a serious problem in recent years. Marine sponges are a rich source of bioactive compounds, and many species can be useful for the development of new antimicrobial drugs. In the present study, 49 CNS strains were isolated from bovine mastitis cases from 21 different dairy herds kept at farms in Southeast Brazil. Strains were analyzed for antimicrobial susceptibility and mecA gene detection. Fifty-nine percent of the CNS strains were resistant to at least one of the drugs tested and 12.2% were classified as multiresistant. Three strains carried the mecA gene, confering resistance to the betalactamic antibiotics. In addition, the CNS strains were submitted to in vitro screening for antimicrobial activities of extracts from marine sponges. Extracts from the sponge species Cinachyrella sp., Haliclona sp. and Petromica citrina showed antibacterial activity against 61% of the CNS strains, including strains resistant to conventional antibiotics. Extracts from P. citrina showed the largest spectrum of inhibitory activity. The aqueous extract inhibited 51% of the CNS strains and presented a bactericidal effect over susceptible and multiresistant-bacteria at a minimal inhibitory concentration of 1.024 mg/ml. ... Mostrar Tudo |
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Palavras-Chave: |
Atividade antibacteriana; Bacteria resistente a antibiotico; Coagulase-negative staphylococci; Esponja marinha; Mastite bovina. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02495naa a2200265 a 4500
001 1942237
005 2023-03-24
008 2012 bl uuuu u00u1 u #d
100 1 $aLAPORT, M. S.
245 $aAntimicrobial activity of marine sponges against coagulase-negative staphylococci isolated from bovine mastitis.$h[electronic resource]
260 $c2012
520 $aBovine mastitis remains worldwide a major challenge for the dairy industry despite the widespread implementation of control strategies. The increasing number of coagulasenegative staphylococci (CNS) causing mastitis and of bacteria resistant to conventional antibiotics has become a serious problem in recent years. Marine sponges are a rich source of bioactive compounds, and many species can be useful for the development of new antimicrobial drugs. In the present study, 49 CNS strains were isolated from bovine mastitis cases from 21 different dairy herds kept at farms in Southeast Brazil. Strains were analyzed for antimicrobial susceptibility and mecA gene detection. Fifty-nine percent of the CNS strains were resistant to at least one of the drugs tested and 12.2% were classified as multiresistant. Three strains carried the mecA gene, confering resistance to the betalactamic antibiotics. In addition, the CNS strains were submitted to in vitro screening for antimicrobial activities of extracts from marine sponges. Extracts from the sponge species Cinachyrella sp., Haliclona sp. and Petromica citrina showed antibacterial activity against 61% of the CNS strains, including strains resistant to conventional antibiotics. Extracts from P. citrina showed the largest spectrum of inhibitory activity. The aqueous extract inhibited 51% of the CNS strains and presented a bactericidal effect over susceptible and multiresistant-bacteria at a minimal inhibitory concentration of 1.024 mg/ml. This study shows the potential of marine sponges as new sources of antibiotics and disinfectants for the control of CNS involved in bovine mastitis.
653 $aAtividade antibacteriana
653 $aBacteria resistente a antibiotico
653 $aCoagulase-negative staphylococci
653 $aEsponja marinha
653 $aMastite bovina
700 1 $aMARINHO, P. R.
700 1 $aSANTOS, O. C. DA S.
700 1 $aALMEIDA, P. DE
700 1 $aROMANOS, M. T. V.
700 1 $aMURICY, G.
700 1 $aBRITO, M. A. V. P. e
700 1 $aGIAMBIAGI-DE-MARVAL, M.
773 $tVeterinary Microbiology$gv. 155, p. 362-368, 2012.
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| 6. |  | CARVALHO, J. M. F. C.; PIMENTEL, N. W.; AIRES, P. S. R.; GROSSI DE SÁ, M. F. Efeito das citocininas no superbrotamento do algodoeiro. In: WORKSHOP INTERAÇÃO MOLECULAR PLANTA-PRAGAS, 2., 2007, Brasília, DF. II Workshop Interação Molecular Planta-Praga. Brasília, DF: Embrapa Recursos Genéticos e Biotecnologia, 2007. p. 79-82. (Embrapa Recursos Genéticos e Biotecnologia. Documentos, 229).| Tipo: Artigo em Anais de Congresso / Nota Técnica |
| Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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