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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
23/06/2023 |
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Autoria: |
HIDIROGLOU, M.; HOFFMAN, I.; JENKINS, K. I. |
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Título: |
Selenium distribution and radiotocopherol metabolism in the pregnant ewe and fetal lamb. |
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Ano de publicação: |
1969 |
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Fonte/Imprenta: |
Canadian Journal Physiology Pharmacology, v. 47, n. 11, p. 953-962, Nov. 1969. |
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DOI: |
https://doi.org/10.1139/y69-156 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Selenium concentrations were determined at various stages of gestation in the bodies and fetal tissues of 26 ewes fed a nutritional muscular dystrophy (NMD) producing hay for 2 years. Eight of these ewes were injected intramuscularly with 6 mg selenium 10 days before slaughter. Maternal tissues in general contained more selenium than the corresponding fetal tissues. As might be expected, the injection of selenium enhanced tissue concentrations in both ewes and fetuses. The pattern of selenium concentration in the various tissues was similar in dams and fetuses, with kidneys containing highest amounts. Selenium concentrations in the tissues of both ewes and fetuses did not appear to change with the stage of gestation. A single oral dose of radiotocopherol was administered to each of 10 pregnant ewes which had been fed an NMD-inducing hay for 2 years. Animals were slaughtered at 1, 2, 5, and 13 days after the oral dose of vitamin E. It was found that in the ewes, liver and adrenal tissues had a high rate of tocopherol uptake in the first 24 h. Subsequently, the radioactivity fell sharply with time, whereas in heart, muscle, kidney, and lung tissues, in which the initial uptake was lower, the decrease with time was slower. Relative specific activities between maternal and corresponding fetal tissues tended to decrease with time. The ewes excreted more than 70% of the administered radiotocopherol dose within 4 days, primarily via the feces; urinary excretion was comparatively small. MenosAbstract: Selenium concentrations were determined at various stages of gestation in the bodies and fetal tissues of 26 ewes fed a nutritional muscular dystrophy (NMD) producing hay for 2 years. Eight of these ewes were injected intramuscularly with 6 mg selenium 10 days before slaughter. Maternal tissues in general contained more selenium than the corresponding fetal tissues. As might be expected, the injection of selenium enhanced tissue concentrations in both ewes and fetuses. The pattern of selenium concentration in the various tissues was similar in dams and fetuses, with kidneys containing highest amounts. Selenium concentrations in the tissues of both ewes and fetuses did not appear to change with the stage of gestation. A single oral dose of radiotocopherol was administered to each of 10 pregnant ewes which had been fed an NMD-inducing hay for 2 years. Animals were slaughtered at 1, 2, 5, and 13 days after the oral dose of vitamin E. It was found that in the ewes, liver and adrenal tissues had a high rate of tocopherol uptake in the first 24 h. Subsequently, the radioactivity fell sharply with time, whereas in heart, muscle, kidney, and lung tissues, in which the initial uptake was lower, the decrease with time was slower. Relative specific activities between maternal and corresponding fetal tissues tended to decrease with time. The ewes excreted more than 70% of the administered radiotocopherol dose within 4 days, primarily via the feces; urinary excretio... Mostrar Tudo |
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Palavras-Chave: |
Laboratorio clinico; Patologia clinica. |
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Thesagro: |
Ovino; Prenhez; Selênio; Vitamina E. |
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Thesaurus Nal: |
Ewes; Mineral metabolism; Pregnancy; Ruminant nutrition; Selenium; Sheep. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02383naa a2200301 a 4500
001 1523657
005 2023-06-23
008 1969 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1139/y69-156$2DOI
100 1 $aHIDIROGLOU, M.
245 $aSelenium distribution and radiotocopherol metabolism in the pregnant ewe and fetal lamb.$h[electronic resource]
260 $c1969
520 $aAbstract: Selenium concentrations were determined at various stages of gestation in the bodies and fetal tissues of 26 ewes fed a nutritional muscular dystrophy (NMD) producing hay for 2 years. Eight of these ewes were injected intramuscularly with 6 mg selenium 10 days before slaughter. Maternal tissues in general contained more selenium than the corresponding fetal tissues. As might be expected, the injection of selenium enhanced tissue concentrations in both ewes and fetuses. The pattern of selenium concentration in the various tissues was similar in dams and fetuses, with kidneys containing highest amounts. Selenium concentrations in the tissues of both ewes and fetuses did not appear to change with the stage of gestation. A single oral dose of radiotocopherol was administered to each of 10 pregnant ewes which had been fed an NMD-inducing hay for 2 years. Animals were slaughtered at 1, 2, 5, and 13 days after the oral dose of vitamin E. It was found that in the ewes, liver and adrenal tissues had a high rate of tocopherol uptake in the first 24 h. Subsequently, the radioactivity fell sharply with time, whereas in heart, muscle, kidney, and lung tissues, in which the initial uptake was lower, the decrease with time was slower. Relative specific activities between maternal and corresponding fetal tissues tended to decrease with time. The ewes excreted more than 70% of the administered radiotocopherol dose within 4 days, primarily via the feces; urinary excretion was comparatively small.
650 $aEwes
650 $aMineral metabolism
650 $aPregnancy
650 $aRuminant nutrition
650 $aSelenium
650 $aSheep
650 $aOvino
650 $aPrenhez
650 $aSelênio
650 $aVitamina E
653 $aLaboratorio clinico
653 $aPatologia clinica
700 1 $aHOFFMAN, I.
700 1 $aJENKINS, K. I.
773 $tCanadian Journal Physiology Pharmacology$gv. 47, n. 11, p. 953-962, Nov. 1969.
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| 1. |  | NUNES, E. N.; SOUSA, A. S. B. de; LUCENA, C. M. de; SILVA, S. de M.; LUCENA, R. F. P. de; ALVES, C. A. B.; ALVES, R. E. Pitaia (Hylocereus sp.): Uma revisão para o Brasil. Gaia Scientia, v. 8, n. 1, p. 90-98, 2014.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 3 |
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