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 | Acesso ao texto completo restrito à biblioteca da Embrapa Soja. Para informações adicionais entre em contato com valeria.cardoso@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia; Embrapa Soja. |
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Data corrente: |
15/10/2024 |
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Data da última atualização: |
15/10/2024 |
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Tipo da produção científica: |
Capítulo em Livro Técnico-Científico |
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Autoria: |
MOLINARI, M. D. C.; PAGLIARINI, R. F.; FLORENTINO, L. H.; LIMA, R. N.; ARRAES, F. B. M.; ABBAD, S. V.; FARIAS, M. P.; MERTZ-HENNING, L. M.; RECH FILHO, E. L.; NEPOMUCENO, A. L.; MOLINARI, H. B. C. |
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Afiliação: |
MAYLA DAIANE CORREA MOLINARI, SEMPRE AGTECH/WIN; RENATA FUGANTI PAGLIARINI, PICOLLA SCIENTIFIC CONSULTING; LILIAN HASEGAWA FLORENTINO, CENARGEN; RAYANE NUNES LIMA; FABRÍCIO BARBOSA MONTEIRO ARRAES, SEMPRE AGTECH/WIN; SAMANTHA VIEIRA ABBAD, SEMPRE AGTECH/WIN; MARCELO PICANÇO DE FARIAS, SEMPRE AGTECH/WIN; LILIANE MARCIA MERTZ HENNING, CNPSO; ELIBIO LEOPOLDO RECH FILHO, CENARGEN; ALEXANDRE LIMA NEPOMUCENO, CNPSO; HUGO BRUNO CORREA MOLINARI, SEMPRE AGTECH/WIN. |
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Título: |
Navigating the path from lab to market: regulatory challenges and opportunities for genome editing technologies for agriculture. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
In: CHEN, J.-T; AHMAR, S. (Ed.). Plant genome editing technologies: speed breeding, crop improvement and sustainable agriculture. Singapore: Springer, 2024. (Interdisciplinary Biotechnological Acvances) |
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Páginas: |
p. 25-63 |
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DOI: |
https://doi.org/10.1007/978-981-99-9338-3_2 |
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Idioma: |
Inglês |
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Notas: |
Na Publicação: Elibio Rech. |
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Conteúdo: |
Over recent decades, an array of molecular tools has been applied in plant genome engineering, including TALENs (transcription activator-like effector nucleases), ZFNs (zinc-finger nucleases), and CRISPR/Cas systems (clustered regularly interspaced short palindromic repeats). At present, CRISPR/Cas systems have caught significant industry attention owing to their cost-effectiveness and precision in genomic modulation, thereby serving as a potent tool in plant science research. Importantly, plants subjected to genome editing via CRISPR/Cas systems might not be classified as genetically modified organisms (GMO), which could streamline their acceptance worldwide. Originally discovered as a defense mechanism against plasmids and invading viruses in bacteria and archaea, the CRISPR/Cas system includes two components: the CRISPR ribonucleic acid (crRNA) and the Cas protein. The crRNA guides the Cas protein to a specific (DNA) target sequence. Once there, the protein cleaves the sequence, thereby impeding replication. In relation to plant genome editing, researchers have modified the crRNA to target distinct genome sequences, and the Cas protein has been manipulated to function as either an endonuclease or a base editor. The most frequently used enzymes from the Type II CRISPR/Cas system are CRISPR/Cas9 and CRISPR/Cas12a (Cpf1). CRISPR/Cas systems and other genome editing tools harbor immense potential to revolutionize plant breeding and biotechnology. Nevertheless, their use must undergo stringent regulation to ensure safe and responsible application. The future holds promise for plant genome editing, with safety being a paramount concern for crop gene editing. As such, it is vital to perpetuate research and development in this field to fully exploit its potential advantages for plant science and agriculture because, as this technology advances and new tools emerge, it becomes crucial for governments to keep abreast of cutting-edge scientific progress. This awareness allows for a balance between gene editing benefits and the associated safety and ethical considerations. MenosOver recent decades, an array of molecular tools has been applied in plant genome engineering, including TALENs (transcription activator-like effector nucleases), ZFNs (zinc-finger nucleases), and CRISPR/Cas systems (clustered regularly interspaced short palindromic repeats). At present, CRISPR/Cas systems have caught significant industry attention owing to their cost-effectiveness and precision in genomic modulation, thereby serving as a potent tool in plant science research. Importantly, plants subjected to genome editing via CRISPR/Cas systems might not be classified as genetically modified organisms (GMO), which could streamline their acceptance worldwide. Originally discovered as a defense mechanism against plasmids and invading viruses in bacteria and archaea, the CRISPR/Cas system includes two components: the CRISPR ribonucleic acid (crRNA) and the Cas protein. The crRNA guides the Cas protein to a specific (DNA) target sequence. Once there, the protein cleaves the sequence, thereby impeding replication. In relation to plant genome editing, researchers have modified the crRNA to target distinct genome sequences, and the Cas protein has been manipulated to function as either an endonuclease or a base editor. The most frequently used enzymes from the Type II CRISPR/Cas system are CRISPR/Cas9 and CRISPR/Cas12a (Cpf1). CRISPR/Cas systems and other genome editing tools harbor immense potential to revolutionize plant breeding and biotechnology. Nevertheless, their use must ... Mostrar Tudo |
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Palavras-Chave: |
CRISPR/Cas; Crop breeding. |
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Thesagro: |
Melhoramento Genético Vegetal; Organismo Transgênico; Segurança Alimentar. |
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Thesaurus Nal: |
Food safety; Genetically modified organisms. |
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Categoria do assunto: |
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X Pesquisa, Tecnologia e Engenharia |
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Marc: |
LEADER 03401naa a2200361 a 4500
001 2168068
005 2024-10-15
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1007/978-981-99-9338-3_2$2DOI
100 1 $aMOLINARI, M. D. C.
245 $aNavigating the path from lab to market$bregulatory challenges and opportunities for genome editing technologies for agriculture.$h[electronic resource]
260 $c2024
300 $ap. 25-63
500 $aNa Publicação: Elibio Rech.
520 $aOver recent decades, an array of molecular tools has been applied in plant genome engineering, including TALENs (transcription activator-like effector nucleases), ZFNs (zinc-finger nucleases), and CRISPR/Cas systems (clustered regularly interspaced short palindromic repeats). At present, CRISPR/Cas systems have caught significant industry attention owing to their cost-effectiveness and precision in genomic modulation, thereby serving as a potent tool in plant science research. Importantly, plants subjected to genome editing via CRISPR/Cas systems might not be classified as genetically modified organisms (GMO), which could streamline their acceptance worldwide. Originally discovered as a defense mechanism against plasmids and invading viruses in bacteria and archaea, the CRISPR/Cas system includes two components: the CRISPR ribonucleic acid (crRNA) and the Cas protein. The crRNA guides the Cas protein to a specific (DNA) target sequence. Once there, the protein cleaves the sequence, thereby impeding replication. In relation to plant genome editing, researchers have modified the crRNA to target distinct genome sequences, and the Cas protein has been manipulated to function as either an endonuclease or a base editor. The most frequently used enzymes from the Type II CRISPR/Cas system are CRISPR/Cas9 and CRISPR/Cas12a (Cpf1). CRISPR/Cas systems and other genome editing tools harbor immense potential to revolutionize plant breeding and biotechnology. Nevertheless, their use must undergo stringent regulation to ensure safe and responsible application. The future holds promise for plant genome editing, with safety being a paramount concern for crop gene editing. As such, it is vital to perpetuate research and development in this field to fully exploit its potential advantages for plant science and agriculture because, as this technology advances and new tools emerge, it becomes crucial for governments to keep abreast of cutting-edge scientific progress. This awareness allows for a balance between gene editing benefits and the associated safety and ethical considerations.
650 $aFood safety
650 $aGenetically modified organisms
650 $aMelhoramento Genético Vegetal
650 $aOrganismo Transgênico
650 $aSegurança Alimentar
653 $aCRISPR/Cas
653 $aCrop breeding
700 1 $aPAGLIARINI, R. F.
700 1 $aFLORENTINO, L. H.
700 1 $aLIMA, R. N.
700 1 $aARRAES, F. B. M.
700 1 $aABBAD, S. V.
700 1 $aFARIAS, M. P.
700 1 $aMERTZ-HENNING, L. M.
700 1 $aRECH FILHO, E. L.
700 1 $aNEPOMUCENO, A. L.
700 1 $aMOLINARI, H. B. C.
773 $tIn: CHEN, J.-T; AHMAR, S. (Ed.). Plant genome editing technologies: speed breeding, crop improvement and sustainable agriculture. Singapore: Springer, 2024. (Interdisciplinary Biotechnological Acvances)
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Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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| 13. |  | OMETTO, A. R.; HAUSCHILD, M.; ROMA, W. N. L.; SOUZA, M. P. DE. Sustainable directions for fuel ethanol in Brazil based on Life Cycle Assessment. OMETTO, A. R.; HAUSCHILD, M.; ROMA, W. N. L.; SOUSA, M. P. Sustainable directions for fuel ethanol in Brazil based on Life Cycle Assessment. In: GLOBAL CONFERENCE ON SUSTAINABLE PRODUCT DEVELOPMENT AND LIFE CYCLE ENGINEERING, 2004, Berlin, Germany. Proceedings... Berlin: Uni GmbH, 2004. p. 385-392.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Territorial. |
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| 15. | | PAVAN, A. L. R.; OMETTO, A. R.; ALVARENGA, R. A. F. De; NETO, J. A. De A.; FIGUEIREDO, M. C. B. de; UGAYA, C. M. L. Serviços ecossitêmicos decorrentes do uso da terra. In: UGAYA, C. M. L.; ALMEIDA NETO, J. A. de; FIGUEIREDO, M. C. B. de. (Org.). Recomendação de modelos de avaliação de impacto do ciclo de vida para o contexto brasileiro. Brasília, DF: Instituto Brasileiro de Informação em Ciência e Tecnologia, 2019. Cap. 9 p. 139-162| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 16. | | UGAYA, C. M. L.; NETO, J. A. de A.; ALVARENGA, R. A. F. de; BARRANTES, LETICIA de SANTI.; FIGUEIREDO, M. C. B. de; LIMA, E. G. de; MENDES, N. C.; OLIVEIRA, J. M. de; OMETTO, A. R.; PAVAN, A. L. R.; PEGORARO, L. A. Materiais e métodos. In: UGAYA, C. M. L.; ALMEIDA NETO, J. A. de; FIGUEIREDO, M. C. B. de. (Org.). Recomendação de modelos de avaliação de impacto do ciclo de vida para o contexto brasileiro. Brasília, DF: IBICT, 2019. p. 19-24| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| Registros recuperados : 16 | |
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| Nenhum registro encontrado para a expressão de busca informada. |
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