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Registro Completo |
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
02/08/2017 |
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Data da última atualização: |
09/08/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SCHINKE, C.; MARTINS, T.; QUEIROZ, S. C. do N. de; MELO, I. S. de; REYES, F. G. R. |
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Afiliação: |
CLAUDIA SCHINKE, FEA-UNICAMP; THAMIRES MARTINS, FEA-UNICAMP; SONIA CLAUDIA DO N DE QUEIROZ, CNPMA; ITAMAR SOARES DE MELO, CNPMA; FELIX GUILLERMO REYES REYES, FEA-UNICAMP. |
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Título: |
Antibacterial compounds from marine bacteria, 2010-2015. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Journal of Natural Products, Cincinnati, v. 80, n. 4, p. 1215?1228, 2017. |
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DOI: |
http://dx.doi.org/10.1021/acs.jnatprod.6b00235 |
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Idioma: |
Inglês |
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Conteúdo: |
This review summarizes the reports on antibacterial compounds that have been obtained from marine-derived bacteria during the period 2010?2015. Over 50 active compounds were isolated during this period, most of which (69%) were obtained from Actinobacteria. Several compounds were already known, such as etamycin A (11) and nosiheptide (65), and new experiments with them showed some previously undetected antibacterial activities, highlighting the fact that known natural products may be an important source of new antibacterial leads. New broad-spectrum antibacterial compounds were reported with activity against antibiotic resistant Gram-positive and Gram-negative bacteria. Anthracimycin (33), kocurin (66), gageotetrins A?C(72?74), and gageomacrolactins 1?3(86?88) are examples of compounds that display promising properties and could be leads to new antibiotics. A number of microbes produced mixtures of metabolites sharing similar chemical sca?olds, and structure?activity relationships are discussed. |
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Palavras-Chave: |
Agente antimicrobiano; Bactéria marinha. |
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Thesagro: |
Actinomiceto; Bactéria. |
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Categoria do assunto: |
S Ciências Biológicas |
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Marc: |
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024 7 $ahttp://dx.doi.org/10.1021/acs.jnatprod.6b00235$2DOI
100 1 $aSCHINKE, C.
245 $aAntibacterial compounds from marine bacteria, 2010-2015.$h[electronic resource]
260 $c2017
520 $aThis review summarizes the reports on antibacterial compounds that have been obtained from marine-derived bacteria during the period 2010?2015. Over 50 active compounds were isolated during this period, most of which (69%) were obtained from Actinobacteria. Several compounds were already known, such as etamycin A (11) and nosiheptide (65), and new experiments with them showed some previously undetected antibacterial activities, highlighting the fact that known natural products may be an important source of new antibacterial leads. New broad-spectrum antibacterial compounds were reported with activity against antibiotic resistant Gram-positive and Gram-negative bacteria. Anthracimycin (33), kocurin (66), gageotetrins A?C(72?74), and gageomacrolactins 1?3(86?88) are examples of compounds that display promising properties and could be leads to new antibiotics. A number of microbes produced mixtures of metabolites sharing similar chemical sca?olds, and structure?activity relationships are discussed.
650 $aActinomiceto
650 $aBactéria
653 $aAgente antimicrobiano
653 $aBactéria marinha
700 1 $aMARTINS, T.
700 1 $aQUEIROZ, S. C. do N. de
700 1 $aMELO, I. S. de
700 1 $aREYES, F. G. R.
773 $tJournal of Natural Products, Cincinnati$gv. 80, n. 4, p. 1215?1228, 2017.
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Registro original: |
Embrapa Meio Ambiente (CNPMA) |
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