01710naa a2200229 a 450000100080000000500110000800800410001902400560006010000160011624500840013226000090021652010150022565000170124065000140125765300260127165300220129770000160131970000280133570000190136370000200138277300780140220735092021-08-09       2017    bl uuuu     u00u1 u    #d7 ahttp://dx.doi.org/10.1021/acs.jnatprod.6b002352DOI1 aSCHINKE, C.  aAntibacterial compounds from marine bacteria, 2010-2015.h[electronic resource]  c2017  aThis review summarizes the reports on antibacterial compounds that have been obtained from marine-derived bacteria during the period 2010?2015. Over 50 active compounds were isolated during this period, most of which (69%) were obtained from Actinobacteria. Several compounds were already known, such as etamycin A (11) and nosiheptide (65), and new experiments with them showed some previously undetected antibacterial activities, highlighting the fact that known natural products may be an important source of new antibacterial leads. New broad-spectrum antibacterial compounds were reported with activity against antibiotic resistant Gram-positive and Gram-negative bacteria. Anthracimycin (33), kocurin (66), gageotetrins A?C(72?74), and gageomacrolactins 1?3(86?88) are examples of compounds that display promising properties and could be leads to new antibiotics. A number of microbes produced mixtures of metabolites sharing similar chemical sca?olds, and structure?activity relationships are discussed.  aActinomiceto  aBactéria  aAgente antimicrobiano  aBactéria marinha1 aMARTINS, T.1 aQUEIROZ, S. C. do N. de1 aMELO, I. S. de1 aREYES, F. G. R.  tJournal of Natural Products, Cincinnatigv. 80, n. 4, p. 1215?1228, 2017.