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Registro Completo |
Biblioteca(s): |
Embrapa Agricultura Digital. |
Data corrente: |
21/01/2016 |
Data da última atualização: |
22/06/2016 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
TIZIOTO, P.; COUTINHO, L. L.; DECKER, J. E.; SCHNABEL, R. D.; ROSA, C. O.; OLIVEIRA, P. S. N.; SOUZA, M. M.; MOURÃO, G. B.; TULLIO, R. R.; CHAVES, A. S.; LANNA, D. P. D.; ZERLOTINI NETO, A.; MUDADU, M. A.; TAYLOR, J. F.; REGITANO, L. C. A. |
Afiliação: |
POLYANA TIZIOTO, CPPSE, University of Missouri Columbia; LUIZ L. COUTINHO, Esalq/USP; JARED E. DECKER, University of Missouri Columbia; ROBERT D. SCHNABEL, University of Missouri Columbia; KAMILA O. ROSA, Unesp Jaboticabal; PRISCILA S. N. OLIVEIRA, UFSCar; MARCELA M. SOUZA, UFSCar; GERSON B. MOURÃO, Esalq/USP; RYMER RAMIZ TULLIO, CPPSE; AMÁLIA S. CHAVES, Esalq/USP; DANTE P. D. LANNA, Esalq/USP; ADHEMAR ZERLOTINI NETO, CNPTIA; MAURICIO DE ALVARENGA MUDADU, CPPSE; JEREMY F. TAYLOR, University of Missouri Columbia; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
Global liver gene expression differences in Nelore steers with divergent residual feed intake phenotypes. |
Ano de publicação: |
2015 |
Fonte/Imprenta: |
BMC Genomics, London, v. 16, p. 1-14, 2015. |
DOI: |
DOI 10.1186/s12864-015-1464-x |
Idioma: |
Inglês |
Conteúdo: |
Background: Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock remains poorly understood. Recent developments in molecular genetics, such as platforms for genome-wide genotyping and sequencing, provide an opportunity to identify genes and pathways that influence production traits. It is known that transcriptional networks influence feed efficiency-related traits such as growth and energy balance. This study sought to identify differentially expressed genes in animals genetically divergent for Residual Feed Intake (RFI), using RNA sequencing methodology (RNA-seq) to obtain information from genome-wide expression profiles in the liver tissues of Nelore cattle. Results: Differential gene expression analysis between high Residual Feed Intake (HRFI, inefficient) and low Residual Feed Intake (LRFI, efficient) groups was performed to provide insights into the molecular mechanisms that underlie feed efficiency-related traits in beef cattle. A total of 112 annotated genes were identified as being differentially expressed between animals with divergent RFI phenotypes. These genes are involved in ion transport and metal ion binding; act as membrane or transmembrane proteins; and belong to gene clusters that are likely related to the transport and catalysis of molecules through the cell membrane and essential mechanisms of nutrient absorption. Genes with functions in cellular signaling, growth and proliferation, cell death and survival were also differentially expressed. Among the over-represented pathways were drug or xenobiotic metabolism, complement and coagulation cascades, NRF2-mediated oxidative stress, melatonin degradation and glutathione metabolism. Conclusions: Our data provide new insights and perspectives on the genetic basis of feed efficiency in cattle. Some previously identified mechanisms were supported and new pathways controlling feed efficiency in Nelore cattle were discovered. We potentially identified genes and pathways that play key roles in hepatic metabolic adaptations to oxidative stress such as those involved in antioxidant mechanisms. These results improve our understanding of the metabolic mechanisms underlying feed efficiency in beef cattle and will help develop strategies for selection towards the desired phenotype. MenosBackground: Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock remains poorly understood. Recent developments in molecular genetics, such as platforms for genome-wide genotyping and sequencing, provide an opportunity to identify genes and pathways that influence production traits. It is known that transcriptional networks influence feed efficiency-related traits such as growth and energy balance. This study sought to identify differentially expressed genes in animals genetically divergent for Residual Feed Intake (RFI), using RNA sequencing methodology (RNA-seq) to obtain information from genome-wide expression profiles in the liver tissues of Nelore cattle. Results: Differential gene expression analysis between high Residual Feed Intake (HRFI, inefficient) and low Residual Feed Intake (LRFI, efficient) groups was performed to provide insights into the molecular mechanisms that underlie feed efficiency-related traits in beef cattle. A total of 112 annotated genes were identified as being differentially expressed between animals with divergent RFI phenotypes. These genes are involved in ion transport and metal ion binding; act as membrane or transmembrane proteins; and belong to gene clusters that are likely related to the transport and catalysis of molecules through the cell membrane and essential mechanisms of nutrient... Mostrar Tudo |
Palavras-Chave: |
Bioinformática; Feed efficiency; RFI; Sequenciamento genético; Transcriptoma. |
Thesagro: |
Bos Indicus. |
Thesaurus Nal: |
Bioinformatics; Feed conversion; Transcriptomics; Zebu. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/138317/1/Global-liver-Tizioto.pdf
|
Marc: |
LEADER 03613naa a2200421 a 4500 001 2034697 005 2016-06-22 008 2015 bl uuuu u00u1 u #d 024 7 $aDOI 10.1186/s12864-015-1464-x$2DOI 100 1 $aTIZIOTO, P. 245 $aGlobal liver gene expression differences in Nelore steers with divergent residual feed intake phenotypes.$h[electronic resource] 260 $c2015 520 $aBackground: Efficiency of feed utilization is important for animal production because it can reduce greenhouse gas emissions and improve industry profitability. However, the genetic basis of feed utilization in livestock remains poorly understood. Recent developments in molecular genetics, such as platforms for genome-wide genotyping and sequencing, provide an opportunity to identify genes and pathways that influence production traits. It is known that transcriptional networks influence feed efficiency-related traits such as growth and energy balance. This study sought to identify differentially expressed genes in animals genetically divergent for Residual Feed Intake (RFI), using RNA sequencing methodology (RNA-seq) to obtain information from genome-wide expression profiles in the liver tissues of Nelore cattle. Results: Differential gene expression analysis between high Residual Feed Intake (HRFI, inefficient) and low Residual Feed Intake (LRFI, efficient) groups was performed to provide insights into the molecular mechanisms that underlie feed efficiency-related traits in beef cattle. A total of 112 annotated genes were identified as being differentially expressed between animals with divergent RFI phenotypes. These genes are involved in ion transport and metal ion binding; act as membrane or transmembrane proteins; and belong to gene clusters that are likely related to the transport and catalysis of molecules through the cell membrane and essential mechanisms of nutrient absorption. Genes with functions in cellular signaling, growth and proliferation, cell death and survival were also differentially expressed. Among the over-represented pathways were drug or xenobiotic metabolism, complement and coagulation cascades, NRF2-mediated oxidative stress, melatonin degradation and glutathione metabolism. Conclusions: Our data provide new insights and perspectives on the genetic basis of feed efficiency in cattle. Some previously identified mechanisms were supported and new pathways controlling feed efficiency in Nelore cattle were discovered. We potentially identified genes and pathways that play key roles in hepatic metabolic adaptations to oxidative stress such as those involved in antioxidant mechanisms. These results improve our understanding of the metabolic mechanisms underlying feed efficiency in beef cattle and will help develop strategies for selection towards the desired phenotype. 650 $aBioinformatics 650 $aFeed conversion 650 $aTranscriptomics 650 $aZebu 650 $aBos Indicus 653 $aBioinformática 653 $aFeed efficiency 653 $aRFI 653 $aSequenciamento genético 653 $aTranscriptoma 700 1 $aCOUTINHO, L. L. 700 1 $aDECKER, J. E. 700 1 $aSCHNABEL, R. D. 700 1 $aROSA, C. O. 700 1 $aOLIVEIRA, P. S. N. 700 1 $aSOUZA, M. M. 700 1 $aMOURÃO, G. B. 700 1 $aTULLIO, R. R. 700 1 $aCHAVES, A. S. 700 1 $aLANNA, D. P. D. 700 1 $aZERLOTINI NETO, A. 700 1 $aMUDADU, M. A. 700 1 $aTAYLOR, J. F. 700 1 $aREGITANO, L. C. A. 773 $tBMC Genomics, London$gv. 16, p. 1-14, 2015.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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Biblioteca(s): |
Embrapa Alimentos e Territórios. |
Data corrente: |
09/05/2024 |
Data da última atualização: |
09/05/2024 |
Tipo da produção científica: |
Artigo de Divulgação na Mídia |
Autoria: |
ARAUJO, G. P. de; CAPELLA, A. P.; SCHNEIDER, F. |
Afiliação: |
GUSTAVO PORPINO DE ARAUJO, CNAT; ALBERTO PACHECO CAPELLA, PROGRAMA DA ONU PARA O MEIO AMBIENTE; FELICITAS SCHNEIDER, INSTITUTO THÜNEN. |
Título: |
As coalizões contra o desperdício de alimentos. |
Ano de publicação: |
2024 |
Fonte/Imprenta: |
Nexo, 21 abr. 2024. |
Páginas: |
3 p. |
Idioma: |
Português |
Notas: |
https://www.nexojornal.com.br/as-coalizoes-contra-o-desperdicio-de-alimentos |
Conteúdo: |
Reduzir o desperdício de alimentos é uma ação com potencial de ganhos ambientais, sociais e econômicos. A redução das emissões de gases de efeito estufa, oportunidades de negócios de impacto social e a ampliação do acesso a alimentos saudáveis são alguns dos muitos impactos positivos alinhados à meta do ODS (Objetivo de Desenvolvimento Sustentável) 12.3. |
Palavras-Chave: |
Aterros sanitários; Circularidade; Courtauld Commitment; Desperdício de alimentos; Desperdício no varejo; End Food Wast Australia; Estratégia Alimentação Saudável nas Cidades; Estratégia Nacional de Resíduos Orgânicos Urbanos; Estresse hídrico; Perdas no campo; Redução de emissões de metano; Resíduos domésticos. |
Categoria do assunto: |
D Governo, Leis e Regulamentações |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1164176/1/CoalizoesContraDesperdicio.pdf
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Marc: |
LEADER 01359nam a2200301 a 4500 001 2164176 005 2024-05-09 008 2024 bl uuuu u00u1 u #d 100 1 $aARAUJO, G. P. de 245 $aAs coalizões contra o desperdício de alimentos.$h[electronic resource] 260 $aNexo, 21 abr. 2024.$c2024 300 $a3 p. 500 $ahttps://www.nexojornal.com.br/as-coalizoes-contra-o-desperdicio-de-alimentos 520 $aReduzir o desperdício de alimentos é uma ação com potencial de ganhos ambientais, sociais e econômicos. A redução das emissões de gases de efeito estufa, oportunidades de negócios de impacto social e a ampliação do acesso a alimentos saudáveis são alguns dos muitos impactos positivos alinhados à meta do ODS (Objetivo de Desenvolvimento Sustentável) 12.3. 653 $aAterros sanitários 653 $aCircularidade 653 $aCourtauld Commitment 653 $aDesperdício de alimentos 653 $aDesperdício no varejo 653 $aEnd Food Wast Australia 653 $aEstratégia Alimentação Saudável nas Cidades 653 $aEstratégia Nacional de Resíduos Orgânicos Urbanos 653 $aEstresse hídrico 653 $aPerdas no campo 653 $aRedução de emissões de metano 653 $aResíduos domésticos 700 1 $aCAPELLA, A. P. 700 1 $aSCHNEIDER, F.
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