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Registro Completo |
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Biblioteca(s): |
Ebooks. |
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Data corrente: |
07/01/2011 |
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Data da última atualização: |
16/06/2011 |
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Autoria: |
BILEZIKIAN, J. P.; RAISZ, L. G.; MARTIN, T. J. |
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Afiliação: |
John P. Bilezikian; Lawrence Gideon Raisz; T. John Martin. |
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Título: |
Principles of bone biology |
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Edição: |
3rd ed. / |
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Ano de publicação: |
2008 |
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Fonte/Imprenta: |
Amsterdam; London: Elsevier, 2008. |
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Páginas: |
2 v. (xxiv, 1942, liv p.) : |
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Descrição Física: |
ill. (some col.) ;29 cm. |
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ISBN: |
9780123738844 |
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Idioma: |
Inglês |
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Conteúdo: |
Provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. It is the most comprehensive, complete, up-to-date source of information on all aspects of bones and bone biology in one convenient source. It takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. *Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants.it is all in one source written by the experts in the field. *THE essential resource for anyone involved in the study of bones and bone diseases. *Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. *Readers can easily search and locate information quickly as it will be online with this new edition. |
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Thesaurus Nal: |
bones. |
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Categoria do assunto: |
-- |
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URL: |
https://www.sciencedirect.com/science/book/9780123738844
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Marc: |
LEADER 01602nam a2200181 a 4500
001 1872161
005 2011-06-16
008 2008 bl uuuu u0uu1 u #d
020 $a9780123738844
100 1 $aBILEZIKIAN, J. P.
245 $aPrinciples of bone biology$h[electronic resource]
250 $a3rd ed. /
260 $aAmsterdam; London: Elsevier$c2008
300 $a2 v. (xxiv, 1942, liv p.) :$cill. (some col.) ;29 cm.
520 $aProvides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. It is the most comprehensive, complete, up-to-date source of information on all aspects of bones and bone biology in one convenient source. It takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. *Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants.it is all in one source written by the experts in the field. *THE essential resource for anyone involved in the study of bones and bone diseases. *Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. *Readers can easily search and locate information quickly as it will be online with this new edition.
650 $abones
700 1 $aRAISZ, L. G.
700 1 $aMARTIN, T. J.
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Registro original: |
Ebooks (Ebooks) |
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Nenhum exemplar cadastrado para este documento. |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Meio Ambiente. Para informações adicionais entre em contato com cnpma.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
18/12/2013 |
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Data da última atualização: |
28/02/2014 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
MELO, I. S. de; SANTOS, S. N.; ROSA, L. H.; PARMA, M. M.; SILVA, L. J.; QUEIROZ, S. C. do N. de; PELLIZARI, V. H. |
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Afiliação: |
ITAMAR SOARES DE MELO, CNPMA; SUIKINAI NOBRE SANTOS, ESALQ-USP; LUIZ HENRIQUE ROSA, ICB-UFMG; MARCIA MARIA PARMA, CNPMA; LEONARDO J SILVA; SONIA CLAUDIA DO NASCIMENTO DE QUEIROZ, CNPMA; VIVAN HELENA PELLIZARI, IO-USP. |
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Título: |
Isolation and biological activities of an endophytic Mortierella alpina strain from the Antarctic moss Schistidium antarctici. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Extremophiles, Tokyo, v. 18, n. 1, p. 15-23, 2014. |
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Idioma: |
Inglês |
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Conteúdo: |
The Antarctic endophytic fungus (strain ITA1-CCMA 952) was isolated from the moss Schistidium antarctici found in Admiralty Bay, King George Island, Antarctica. Strain ITA1-CCMA 952 was assigned to the specie Mortierella alpina by phylogenetic analysis based on 18S rRNA gene sequences. This strain produces high levels of polyunsaturated fatty acids (PUFAs), including y-(gamma) linolenic acid and arachidonic acid, which when combined represents 48.3 % of the total fatty acid content. Fungal extracts demonstrated strong antioxidant activity with the EC50 value of 48.7 lg mL-1 and also a strong antibacterial activity, mainly against the following bacteria: Escherichia coli, with a MIC of 26.9 lg mL-1 and Pseudomonas aeruginosa and Enterococcus faecalis, both with a MIC of 107 lg mL-1. A GC-MS analysis of the chloroform fraction obtained from the crude extract revealed the presence of potential antimicrobials (Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl) and Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(phenylmethyl)) as the major compounds. Therefore, the M. alpina strain ITA1-CCMA 952 is a promising fungus for the biotechnological production of antibiotics, antioxidant substances and PUFAs. This study highlights the need for more research in extreme environments, such as Antarctica. |
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Palavras-Chave: |
Antibacterial activity; PUFAs; Pyrrolopyrazine alkaloids; Schistidium antarctici. |
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Thesagro: |
Bactéria; Fungo. |
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Thesaurus NAL: |
Antarctica; Antibacterial properties; Entomopathogenic fungi; Mortierella. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02258naa a2200313 a 4500
001 1974294
005 2014-02-28
008 2014 bl uuuu u00u1 u #d
100 1 $aMELO, I. S. de
245 $aIsolation and biological activities of an endophytic Mortierella alpina strain from the Antarctic moss Schistidium antarctici.$h[electronic resource]
260 $c2014
520 $aThe Antarctic endophytic fungus (strain ITA1-CCMA 952) was isolated from the moss Schistidium antarctici found in Admiralty Bay, King George Island, Antarctica. Strain ITA1-CCMA 952 was assigned to the specie Mortierella alpina by phylogenetic analysis based on 18S rRNA gene sequences. This strain produces high levels of polyunsaturated fatty acids (PUFAs), including y-(gamma) linolenic acid and arachidonic acid, which when combined represents 48.3 % of the total fatty acid content. Fungal extracts demonstrated strong antioxidant activity with the EC50 value of 48.7 lg mL-1 and also a strong antibacterial activity, mainly against the following bacteria: Escherichia coli, with a MIC of 26.9 lg mL-1 and Pseudomonas aeruginosa and Enterococcus faecalis, both with a MIC of 107 lg mL-1. A GC-MS analysis of the chloroform fraction obtained from the crude extract revealed the presence of potential antimicrobials (Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl) and Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(phenylmethyl)) as the major compounds. Therefore, the M. alpina strain ITA1-CCMA 952 is a promising fungus for the biotechnological production of antibiotics, antioxidant substances and PUFAs. This study highlights the need for more research in extreme environments, such as Antarctica.
650 $aAntarctica
650 $aAntibacterial properties
650 $aEntomopathogenic fungi
650 $aMortierella
650 $aBactéria
650 $aFungo
653 $aAntibacterial activity
653 $aPUFAs
653 $aPyrrolopyrazine alkaloids
653 $aSchistidium antarctici
700 1 $aSANTOS, S. N.
700 1 $aROSA, L. H.
700 1 $aPARMA, M. M.
700 1 $aSILVA, L. J.
700 1 $aQUEIROZ, S. C. do N. de
700 1 $aPELLIZARI, V. H.
773 $tExtremophiles, Tokyo$gv. 18, n. 1, p. 15-23, 2014.
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Embrapa Meio Ambiente (CNPMA) |
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