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 | Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Leite. Para informações adicionais entre em contato com cnpgl.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
06/01/2020 |
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Data da última atualização: |
06/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ZANETTE, R. S. S.; ALMEIDA, L. B. F. DE; SOUZA, N. L. G. D.; ALMEIDA, C. G. DE; OLIVEIRA, L. F. C. DE; MATOS, ELYABE M. DE; GERN, J. C.; BRANDAO, H. de M.; MUNK, M. |
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Afiliação: |
Rafaella S. S. Zanette; Leonara B. F. de Almeida; Nelson L. G. D. Souza; Camila G. de Almeida; Luiz F. C. de Oliveira; Elyabe M. de Matos; JULIANA CARINE GERN, CNPGL; HUMBERTO DE MELLO BRANDAO, CNPGL; Michele Munk. |
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Título: |
Cotton cellulose nanofiber/chitosan nanocomposite: characterization and evaluation of cytocompatibility. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
Journal of Biomaterials Science, Polymer Edition, v. 30, n. 16, p. 1489-1504, 2019. |
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DOI: |
https://doi.org/10.1080/09205063.2019.1646627 |
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Idioma: |
Inglês |
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Conteúdo: |
Cellulose is a renewable polymer quite abundant on the Earth and very attractive for applications in the construction of eco-friendly biomedical products. The aim of this study was to investigate the chemical-physical characteristics of cotton cellulose nanofiber (CCN)/chitosan nanocomposite and its cytocompatibility with human embryonic kidney cells. First, the chemical composition, swelling ratio and surface topography of the nanocomposite were evaluated. Cytocompatibility was then assessed through spreading, proliferation and viability of cells. The experimental results showed that the CCN was an effective nanomaterial agent for increasing the roughness surface of chitosan film. Cell proliferation and changes in cell morphology indicated that the nanocomposite led to improved cell spreading and growth. Cell viability did not decrease after 24 h. However, the cell survival on the nanocomposite was affected at 72 h. The results indicate that CCN/chitosan nanocomposite could be a promising biocompatible biomaterial for biomedical applications. |
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Palavras-Chave: |
Biomaterials; Biopolymer; In vitro cell culture; Nanotopography; Polymeric nanomaterials. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02008naa a2200289 a 4500
001 2118188
005 2024-02-06
008 2019 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1080/09205063.2019.1646627$2DOI
100 1 $aZANETTE, R. S. S.
245 $aCotton cellulose nanofiber/chitosan nanocomposite$bcharacterization and evaluation of cytocompatibility.$h[electronic resource]
260 $c2019
520 $aCellulose is a renewable polymer quite abundant on the Earth and very attractive for applications in the construction of eco-friendly biomedical products. The aim of this study was to investigate the chemical-physical characteristics of cotton cellulose nanofiber (CCN)/chitosan nanocomposite and its cytocompatibility with human embryonic kidney cells. First, the chemical composition, swelling ratio and surface topography of the nanocomposite were evaluated. Cytocompatibility was then assessed through spreading, proliferation and viability of cells. The experimental results showed that the CCN was an effective nanomaterial agent for increasing the roughness surface of chitosan film. Cell proliferation and changes in cell morphology indicated that the nanocomposite led to improved cell spreading and growth. Cell viability did not decrease after 24 h. However, the cell survival on the nanocomposite was affected at 72 h. The results indicate that CCN/chitosan nanocomposite could be a promising biocompatible biomaterial for biomedical applications.
653 $aBiomaterials
653 $aBiopolymer
653 $aIn vitro cell culture
653 $aNanotopography
653 $aPolymeric nanomaterials
700 1 $aALMEIDA, L. B. F. DE
700 1 $aSOUZA, N. L. G. D.
700 1 $aALMEIDA, C. G. DE
700 1 $aOLIVEIRA, L. F. C. DE
700 1 $aMATOS, ELYABE M. DE
700 1 $aGERN, J. C.
700 1 $aBRANDAO, H. de M.
700 1 $aMUNK, M.
773 $tJournal of Biomaterials Science, Polymer Edition$gv. 30, n. 16, p. 1489-1504, 2019.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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| Registros recuperados : 24 | |
| 21. |  | MUNK, M.; ZANETTE, R. de S. S.; CAMARGO, L. S. de A.; SOUZA, N. L. G. D. de; ALMEIDA, C. G. de; GERN, J. C.; GUIMARAES, A. S.; LADEIRA, L. O.; OLIVEIRA, L. F. C. de; BRANDAO, H. de M. Using carbon nanotubes to deliver genes to hard-to-transfect mammalian primary fibroblast cells. Biomedical Physics & Engineering Express, v. 3, n. 4, 045002, 2017.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: B - 5 |
| Biblioteca(s): Embrapa Gado de Leite. |
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| 22. | | GREGO, C. R.; RODRIGUES, C. A. G.; NOGUEIRA, S. F.; GIMENES, F. M. A.; OLIVEIRA, A. DE; ALMEIDA, C. G. F. DE; FURTADO, A. L. dos S.; DEMARCHI, J. J. A. DE A. Variabilidade espacial do solo e da biomassa epígea de pastagem, identificada por meio de geostatística. Pesquisa Agropecuária Brasileira, Brasilia, DF, v. 47, n. 9, p. 1404-1412, set. 2012.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Territorial; Embrapa Unidades Centrais. |
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| 23. | | AMARAL, D. L.; ZANETTE, R. S.; ALMEIDA, C. G.; ALMEIDA, L. B.; OLIVEIRA, L. F.; MARCOMINI, R. F.; NOGUEIRA, B. V.; SANTOS, M. O.; BRANDAO, H. de M.; MARANDUBA, C. M. C.; MUNK, M. In vitro evaluation of barium titanate nanoparticle/alginate 3D scaffold for osteogenic human stem cell differentiation. Biomedical Materials, v. 14, article 035011, 2019.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 2 |
| Biblioteca(s): Embrapa Gado de Leite. |
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| 24. | | SILVA, N. P. da; PEREIRA, E. do C. R. L.; DUARTE, L. M.; FREITAS, J. C. de O.; ALMEIDA, C. G. de; SILVA, T. P. da; MELO, R. C. N.; APOLONIO, A. C. M.; OLIVEIRA, M. A. L. de; BRANDAO, H. de M.; PITTELLA, F.; FABRI, R. L.; TAVARES, G. D.; PINTO, P. de F. Improved anti-Cutibacterium acnes activity of tea tree oil-loaded chitosan-poly(ε-caprolactone) core-shell nanocapsules. Colloids and Surfaces B: Biointerfaces, v. 196, 111371, 2020.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: A - 1 |
| Biblioteca(s): Embrapa Gado de Leite. |
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| Registros recuperados : 24 | |
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