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Registro Completo |
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Biblioteca(s): |
Embrapa Florestas. |
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Data corrente: |
07/06/2024 |
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Data da última atualização: |
08/11/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LEAL, F. C.; UEDA, K. M.; LIMA, T. A. de M. de; FREITAS, R. A. de; HELM, C. V.; MAGALHAES, W. L. E.; MAFRA, M. R.; IGARASHI‑MAFRA, L. |
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Afiliação: |
FERNANDO CASTRO LEAL, UNIVERSIDADE FEDERAL DO PARANÁ; KARINA MAYUMI UEDA, UNIVERSIDADE FEDERAL DO PARANÁ; TIELIDY ANGELINA DE MORAIS DE LIMA, TECHNOLOGICAL UNIVERSITY OF THE SHANNON; RILTON ALVES DE FREITAS, UNIVERSIDADE FEDERAL DO PARANÁ; CRISTIANE VIEIRA HELM, CNPF; WASHINGTON LUIZ ESTEVES MAGALHAES, CNPF; MARCOS R. MAFRA, UNIVERSIDADE FEDERAL DO PARANÁ; LUCIANA IGARASHI‑MAFRA, UNIVERSIDADE FEDERAL DO PARANÁ. |
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Título: |
Pinhão coat (Araucaria angustifolia (Bertol.) Kuntze) nanosuspension as a potential additive in cosmetic formulations with wound healing effect. |
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Ano de publicação: |
2024 |
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Fonte/Imprenta: |
Waste and Biomass Valorization, v. 15, p. 5323-5334, 2024. |
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DOI: |
https://doi.org/10.1007/s12649-024-02427-1 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract Purpose Development of a sustainable route to value pinhão (Araucaria angustifolia (Bertol.) Kuntze) coat through mechani- cal defibrillation process and employment as an additive in cosmetic formulations. Methods The pinhão coat nanosuspension (PCN) was added to the Lanette® base at concentrations of 0.5, 1.0, 1.5, and 2.0%. Subsequently, the PCN-based formulations were evaluated concerning their appearance, physiochemical aspects (pH, spreadability, and stability tests), rheological behavior, cytotoxicity, and wound closure capacity. Results The outcomes showed that the PCN addition conferred a light brown milky color to the lotions, besides decreasing the pH values and increasing the spreadability compared to the control formulations. Related to the rheological analysis, the lotions with PCN displayed pseudoplastic behavior, an aspect of strong gel, and were also stable through the thermomechani- cal analysis. The cell viability analysis showed no cytotoxicity of the PCN-based formulations at concentrations inferior to 0.05 mg/mL. Furthermore, the in vitro scratch wound assay revealed that the presence of PCN (1.5 and 2.0%) promoted a complete wound contraction after 72 h of treatment. Conclusion The study demonstrated a sustainable alternative to apply pinhão by-product in cosmetic formulation with wound-healing effects. |
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Palavras-Chave: |
Citotoxicidade; Compostos bioativos; Rheological behavior; Sustentabilidade; Waste valorization. |
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Thesagro: |
Araucária Angustifólia; Pinhão; Produto Florestal; Resíduo Orgânico. |
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Thesaurus Nal: |
Bioactive compounds; Cytotoxicity. |
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Categoria do assunto: |
Q Alimentos e Nutrição Humana |
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Marc: |
LEADER 02471naa a2200349 a 4500
001 2164763
005 2024-11-08
008 2024 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1007/s12649-024-02427-1$2DOI
100 1 $aLEAL, F. C.
245 $aPinhão coat (Araucaria angustifolia (Bertol.) Kuntze) nanosuspension as a potential additive in cosmetic formulations with wound healing effect.$h[electronic resource]
260 $c2024
520 $aAbstract Purpose Development of a sustainable route to value pinhão (Araucaria angustifolia (Bertol.) Kuntze) coat through mechani- cal defibrillation process and employment as an additive in cosmetic formulations. Methods The pinhão coat nanosuspension (PCN) was added to the Lanette® base at concentrations of 0.5, 1.0, 1.5, and 2.0%. Subsequently, the PCN-based formulations were evaluated concerning their appearance, physiochemical aspects (pH, spreadability, and stability tests), rheological behavior, cytotoxicity, and wound closure capacity. Results The outcomes showed that the PCN addition conferred a light brown milky color to the lotions, besides decreasing the pH values and increasing the spreadability compared to the control formulations. Related to the rheological analysis, the lotions with PCN displayed pseudoplastic behavior, an aspect of strong gel, and were also stable through the thermomechani- cal analysis. The cell viability analysis showed no cytotoxicity of the PCN-based formulations at concentrations inferior to 0.05 mg/mL. Furthermore, the in vitro scratch wound assay revealed that the presence of PCN (1.5 and 2.0%) promoted a complete wound contraction after 72 h of treatment. Conclusion The study demonstrated a sustainable alternative to apply pinhão by-product in cosmetic formulation with wound-healing effects.
650 $aBioactive compounds
650 $aCytotoxicity
650 $aAraucária Angustifólia
650 $aPinhão
650 $aProduto Florestal
650 $aResíduo Orgânico
653 $aCitotoxicidade
653 $aCompostos bioativos
653 $aRheological behavior
653 $aSustentabilidade
653 $aWaste valorization
700 1 $aUEDA, K. M.
700 1 $aLIMA, T. A. de M. de
700 1 $aFREITAS, R. A. de
700 1 $aHELM, C. V.
700 1 $aMAGALHAES, W. L. E.
700 1 $aMAFRA, M. R.
700 1 $aIGARASHI‑MAFRA, L.
773 $tWaste and Biomass Valorization$gv. 15, p. 5323-5334, 2024.
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Registro original: |
Embrapa Florestas (CNPF) |
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