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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
16/06/1997 |
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Data da última atualização: |
18/07/2023 |
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Autoria: |
JOST, C. C.; SHERMAN, D. M.; THOMPSON, E. F.; HESSELTON, R. M. |
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Título: |
Kamala (Mallotus philippinensis) fruit is ineffective as an anthelminthic against gastrointestinal nematodes in goats indigenous to Balochistan, Pakistan. |
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Ano de publicação: |
1996 |
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Fonte/Imprenta: |
Small Ruminant Research, v. 20, n. 2, p. 147-153, May, 1996. |
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DOI: |
https://doi.org/10.1016/0921-4488(95)00791-1 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Single dose oral treatments of kamala, the dried, powdered fruit of Mallotus philippinensis (250, 375, 500 and 750 mg kg?1 liveweight), were compared with a single dose of fenbendazole (Panacur®) (10 mg kg?1 liveweight, as recommended by the manufacturer) to determine the relative effectiveness of each against gastrointestinal nematodes with a direct life-cycle. Twenty-eight castrated male goats were made parasite free and then inoculated with mixed cultures of infective, direct life-cycle nematode larvae. The fecal eggs per gram (EPG) counts for the groups treated with 250 and 375 mg kg?1 of kamala did not significantly (P > 0.05) drop (pre-treatment means 2071 ± 1149 and 2245 ± 1130, respectively) over a 26 day period (day 26 means 3217 ± 1604 and 2942 ± 2076, respectively). The EPG counts for the groups treated with 500 and 750 mg kg?1of kamala did not significantly (P > 0.05) drop (pre-treatment means 534 ± 212 and 9440 ± 8693, respectively) overa 15day period (day 15 means 338 ± 158 and 2202 ± 1930, respectively). Fenbendazole affected a significant decrease (P < 0.001) in EPG counts from pre-treatment values (mean 1864 ± 1030) after a period of 5 days (mean 0.0 ± 0.0). Although interviews conducted in Quetta, Pakistan, indicate that there is a great dependency upon kamala as a general anthelminthic in the area, it is concluded that kamala is not effective in eliminating direct life-cycle gastrointestinal nematodes in goats. Therefore, kamala should not be used alone as a treatment for nematode infections of the gastrointestinal tract. MenosAbstract: Single dose oral treatments of kamala, the dried, powdered fruit of Mallotus philippinensis (250, 375, 500 and 750 mg kg?1 liveweight), were compared with a single dose of fenbendazole (Panacur®) (10 mg kg?1 liveweight, as recommended by the manufacturer) to determine the relative effectiveness of each against gastrointestinal nematodes with a direct life-cycle. Twenty-eight castrated male goats were made parasite free and then inoculated with mixed cultures of infective, direct life-cycle nematode larvae. The fecal eggs per gram (EPG) counts for the groups treated with 250 and 375 mg kg?1 of kamala did not significantly (P > 0.05) drop (pre-treatment means 2071 ± 1149 and 2245 ± 1130, respectively) over a 26 day period (day 26 means 3217 ± 1604 and 2942 ± 2076, respectively). The EPG counts for the groups treated with 500 and 750 mg kg?1of kamala did not significantly (P > 0.05) drop (pre-treatment means 534 ± 212 and 9440 ± 8693, respectively) overa 15day period (day 15 means 338 ± 158 and 2202 ± 1930, respectively). Fenbendazole affected a significant decrease (P < 0.001) in EPG counts from pre-treatment values (mean 1864 ± 1030) after a period of 5 days (mean 0.0 ± 0.0). Although interviews conducted in Quetta, Pakistan, indicate that there is a great dependency upon kamala as a general anthelminthic in the area, it is concluded that kamala is not effective in eliminating direct life-cycle gastrointestinal nematodes in goats. Therefore, kamala should not be use... Mostrar Tudo |
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Palavras-Chave: |
Controle; Kamala; Nematodeos gastrintestinais; Traditional medicines. |
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Thesagro: |
Caprino; Fitoterapia. |
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Thesaurus Nal: |
Anthelmintics; Fenbendazole; Gastrointestinal nematodes; Goat diseases; Goats; Mallotus philippinensis; Medicinal plants; Phytotherapy. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02652naa a2200337 a 4500
001 1522465
005 2023-07-18
008 1996 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/0921-4488(95)00791-1$2DOI
100 1 $aJOST, C. C.
245 $aKamala (Mallotus philippinensis) fruit is ineffective as an anthelminthic against gastrointestinal nematodes in goats indigenous to Balochistan, Pakistan.$h[electronic resource]
260 $c1996
520 $aAbstract: Single dose oral treatments of kamala, the dried, powdered fruit of Mallotus philippinensis (250, 375, 500 and 750 mg kg?1 liveweight), were compared with a single dose of fenbendazole (Panacur®) (10 mg kg?1 liveweight, as recommended by the manufacturer) to determine the relative effectiveness of each against gastrointestinal nematodes with a direct life-cycle. Twenty-eight castrated male goats were made parasite free and then inoculated with mixed cultures of infective, direct life-cycle nematode larvae. The fecal eggs per gram (EPG) counts for the groups treated with 250 and 375 mg kg?1 of kamala did not significantly (P > 0.05) drop (pre-treatment means 2071 ± 1149 and 2245 ± 1130, respectively) over a 26 day period (day 26 means 3217 ± 1604 and 2942 ± 2076, respectively). The EPG counts for the groups treated with 500 and 750 mg kg?1of kamala did not significantly (P > 0.05) drop (pre-treatment means 534 ± 212 and 9440 ± 8693, respectively) overa 15day period (day 15 means 338 ± 158 and 2202 ± 1930, respectively). Fenbendazole affected a significant decrease (P < 0.001) in EPG counts from pre-treatment values (mean 1864 ± 1030) after a period of 5 days (mean 0.0 ± 0.0). Although interviews conducted in Quetta, Pakistan, indicate that there is a great dependency upon kamala as a general anthelminthic in the area, it is concluded that kamala is not effective in eliminating direct life-cycle gastrointestinal nematodes in goats. Therefore, kamala should not be used alone as a treatment for nematode infections of the gastrointestinal tract.
650 $aAnthelmintics
650 $aFenbendazole
650 $aGastrointestinal nematodes
650 $aGoat diseases
650 $aGoats
650 $aMallotus philippinensis
650 $aMedicinal plants
650 $aPhytotherapy
650 $aCaprino
650 $aFitoterapia
653 $aControle
653 $aKamala
653 $aNematodeos gastrintestinais
653 $aTraditional medicines
700 1 $aSHERMAN, D. M.
700 1 $aTHOMPSON, E. F.
700 1 $aHESSELTON, R. M.
773 $tSmall Ruminant Research$gv. 20, n. 2, p. 147-153, May, 1996.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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