02652naa a2200337 a 450000100080000000500110000800800410001902400540006010000160011424501820013026000090031252015980032165000180191965000170193765000310195465000180198565000100200365000280201365000210204165000170206265000120207965000160209165300130210765300110212065300320213165300260216370000190218970000200220870000210222877300650224915224652023-07-18       1996    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1016/0921-4488(95)00791-12DOI1 aJOST, C. C.  aKamala (Mallotus philippinensis) fruit is ineffective as an anthelminthic against gastrointestinal nematodes in goats indigenous to Balochistan, Pakistan.h[electronic resource]  c1996  aAbstract: Single dose oral treatments of kamala, the dried, powdered fruit of Mallotus philippinensis (250, 375, 500 and 750 mg kg?1 liveweight), were compared with a single dose of fenbendazole (Panacur®) (10 mg kg?1 liveweight, as recommended by the manufacturer) to determine the relative effectiveness of each against gastrointestinal nematodes with a direct life-cycle. Twenty-eight castrated male goats were made parasite free and then inoculated with mixed cultures of infective, direct life-cycle nematode larvae. The fecal eggs per gram (EPG) counts for the groups treated with 250 and 375 mg kg?1 of kamala did not significantly (P &gt 0.05) drop (pre-treatment means 2071 ± 1149 and 2245 ± 1130, respectively) over a 26 day period (day 26 means 3217 ± 1604 and 2942 ± 2076, respectively). The EPG counts for the groups treated with 500 and 750 mg kg?1of kamala did not significantly (P &gt 0.05) drop (pre-treatment means 534 ± 212 and 9440 ± 8693, respectively) overa 15day period (day 15 means 338 ± 158 and 2202 ± 1930, respectively). Fenbendazole affected a significant decrease (P &lt 0.001) in EPG counts from pre-treatment values (mean 1864 ± 1030) after a period of 5 days (mean 0.0 ± 0.0). Although interviews conducted in Quetta, Pakistan, indicate that there is a great dependency upon kamala as a general anthelminthic in the area, it is concluded that kamala is not effective in eliminating direct life-cycle gastrointestinal nematodes in goats. Therefore, kamala should not be used alone as a treatment for nematode infections of the gastrointestinal tract.  aAnthelmintics  aFenbendazole  aGastrointestinal nematodes  aGoat diseases  aGoats  aMallotus philippinensis  aMedicinal plants  aPhytotherapy  aCaprino  aFitoterapia  aControle  aKamala  aNematodeos gastrintestinais  aTraditional medicines1 aSHERMAN, D. M.1 aTHOMPSON, E. F.1 aHESSELTON, R. M.  tSmall Ruminant Researchgv. 20, n. 2, p. 147-153, May, 1996.