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Registros recuperados : 37 | |
3. | | FREITAS, M. A.; MACHADO, J. C.; ANDRADE, A. C. Molecular characterization of Stenocarpella macrospora (Earle) Sutton and Stenocarpella maydis (Berk Sutton) isolates. Fitopatologia Brasileira, Brasília, DF, v. 32, supl., p. S307, ago. 2007. Resumo 0995. Edição dos Resumos do XL Congresso Brasileiro de Fitopatologia, Maringá, PR, ago. 2007. Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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5. | | COLETTA FILHO, H. D.; RODRIGUES, C.; TAKITA, M. A.; MACHADO, M. A. Ensaio de patogenicidade da bactéria Xylella fastidiosa, estirpe J1 a 12, em plantas de tabaco. Fitopatologia Brasileira, Brasília, DF, v. 29, supl., p. S48, ago. 2004. Edição dos Resumos do XXXVII Congresso Brasileiro de Fitopatologia, Gramado, RS, ago. 2004. Biblioteca(s): Embrapa Recursos Genéticos e Biotecnologia. |
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6. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHES, L. N.; OLIVEIRA, H. N. Goat biometry in the brazilian southeast region. I. Anglo-Nubian breed; purebred of imported origin and their progeny. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1341. Abstract 55. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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7. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHES, L. N.; OLIVEIRA, H. N. Goat biometry in the Brazilian Southeast region. II. Anglo-Nubian breed-crossbred. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1342. Abstract 56. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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8. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHEZ, L. N.; OLIVEIRA, H. N. Goat biometry in the Brazilian Southeast region. III. Alpine breed - purebred of imported origin and their progeny. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1342-1343. Abstract 57. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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9. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHEZ, L. N.; OLIVEIRA, H. N. Goat biometry in the Brazilian Southeast region. IV. Alpine breed, crossbred. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1343. Abstract 58. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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10. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHEZ, L. N.; OLIVEIRA, H. N. Goat biometry in the Brazilian Southeast region. VIII. Toggenburg breed, crossbred. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1346. Abstract 62. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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11. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHEZ, L. N.; OLIVEIRA, H. N. Goat biometry in the Brazilian Southeast region. VII. Toggenburg breed, purebreed of imported origin and their progeny. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1345. Abstract 61. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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12. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHEZ, L. N.; OLIVEIRA, H. N. Goat biometry in the Brazilian Southeast region. VI. Saanen breed, crossbred. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1344-1345. Abstract 60. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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13. | | CALDAS, R. P.; FERNANDES, M. A.; MACHADO, T. M. M.; SANCHEZ, L. N.; OLIVEIRA, H. N. Goat biometry in the Brazilian Southeast region. V. Saanen breed, purebred of imported origin and their progeny. In: INTERNATIONAL CONFERENCE ON GOATS, 4., 1987, Brasília, DF. Proceedings... Brasília, DF: EMBRAPA-DDT, 1987. v. 2. p. 1344. Abstract 59. Biblioteca(s): Embrapa Caprinos e Ovinos. |
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15. | | WASSERMAN, J. C.; ALMEIDA, A. M.; PEREZ, D. V.; WASSERMAN, M. A.; MACHADO, W. Evaluation of contaminants spreading from sludge piles, applying geochemical fractionation and attenuation of concentrations model in a tropical reservoir. Environmental Monitoring and Assessment, v. 191, n. 7, 426, Jul. 2019. Biblioteca(s): Embrapa Solos. |
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16. | | COUTINHO, E, F.; CARLLOTO, F.; CAPELLARO, T, H.; TESSMER, M, A; MACHADO, N, P. Propagação vegetativa de pessegueiro `eragil´ por alporquia. In: ENCONTRO NACIONAL SOBRE FRUTICULTURA DE CLIMA TEMPERADO, 10., 2007, Fraiburgo. Resumos... Caçador: EPAGRI, Estação Experimental de Caçador, 2007. v. 2 p. 21 Biblioteca(s): Embrapa Clima Temperado. |
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20. | | MARTINS, L. L.; ALMEIDA-SILVA, I.; ROSSATO, M.; MURASHIMA, A. A. B.; HYPPOLITO, M. A.; MACHADO, M. R. F. Macroscopic description of the external and middle ear of paca (Cuniculus paca Linnaeus, 1766). Pesquisa Veterinária Brasileira, Brasília, DF, v. 35, n. 6, p. 583-589, jun. 2015 Biblioteca(s): Embrapa Unidades Centrais. |
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Registros recuperados : 37 | |
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Registro Completo
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
20/04/2010 |
Data da última atualização: |
16/02/2024 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
ALVES, C. C. de S.; AZEVEDO, A. L. S.; RODRIGUES, M. F.; MACHADO, R. P.; SOUZA, M. A.; MACHADO, M. A.; TEIXEIRA, H. C.; FERREIRA, A. P. |
Afiliação: |
CAIO CÉSAR DE SOUZA ALVES, UFJF; ANA LUISA SOUSA AZEVEDO, CNPGL; MICHELE F. RODRIGUES, UFJF; RACHEL P. MACHADO, UFJF; SUPREMA; MARIA A. SOUZA, UFJF; MARCO ANTONIO MACHADO, CNPGL; HENRIQUE C. TEIXEIRA, UFJF; ANA P. FERREIRA, UFJF. |
Título: |
Cellular and humoral immune responses during intrathoracic paracoccidioidomycosis in BALB/c mice. |
Ano de publicação: |
2009 |
Fonte/Imprenta: |
Comparative Immunology, Microbiology and Infectious Discases, v. 32, n. 6, p. 513-525, 2009. |
DOI: |
https://doi.org/10.1016/j.cimid.2008.07.006 |
Idioma: |
Inglês |
Conteúdo: |
Paracoccidioidomycosis is a chronic infection that primarily affects the lungs. Here we investigated cellular and humoral immune responses after intrathoracic Paracoccidioidesbrasiliensis infection in BALB/c mice. P. brasiliensis-colony-forming units (CFUs), fungal DNA and granulomas in lungs increased progressively, peaking at day 90 postinfection (p.i.). IFN-γ production was highest on day 15 p.i., declining thereafter. The kinetics of the NO production was similar to that described for IFN-γ. In contrast, IL-10 increased from day 45 p.i. reaching a peak at day 90. Levels of serum IgG1 were higher than IgG2a between days 30 and 90 p.i. 30% of mice died by day 90 p.i. These data indicate that infection with P. brasiliensis by the intrathoracic route shows high IFN-γ and NO production at day 15 p.i., unable to control multiplication of fungi, which appears to be associated with a progressive increase in IL-10 and in the number and complexity of granulomas. |
Palavras-Chave: |
Antibody response; IFN-y; IL-10; Intrathoracic route. |
Thesaurus NAL: |
Paracoccidioides brasiliensis. |
Categoria do assunto: |
H Saúde e Patologia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/697051/1/Cellular-and-humoral-immune-responses-during-intrathoracic-paracoccidioidomycosis.pdf
|
Marc: |
LEADER 01861naa a2200277 a 4500 001 1697051 005 2024-02-16 008 2009 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1016/j.cimid.2008.07.006$2DOI 100 1 $aALVES, C. C. de S. 245 $aCellular and humoral immune responses during intrathoracic paracoccidioidomycosis in BALB/c mice.$h[electronic resource] 260 $c2009 520 $aParacoccidioidomycosis is a chronic infection that primarily affects the lungs. Here we investigated cellular and humoral immune responses after intrathoracic Paracoccidioidesbrasiliensis infection in BALB/c mice. P. brasiliensis-colony-forming units (CFUs), fungal DNA and granulomas in lungs increased progressively, peaking at day 90 postinfection (p.i.). IFN-γ production was highest on day 15 p.i., declining thereafter. The kinetics of the NO production was similar to that described for IFN-γ. In contrast, IL-10 increased from day 45 p.i. reaching a peak at day 90. Levels of serum IgG1 were higher than IgG2a between days 30 and 90 p.i. 30% of mice died by day 90 p.i. These data indicate that infection with P. brasiliensis by the intrathoracic route shows high IFN-γ and NO production at day 15 p.i., unable to control multiplication of fungi, which appears to be associated with a progressive increase in IL-10 and in the number and complexity of granulomas. 650 $aParacoccidioides brasiliensis 653 $aAntibody response 653 $aIFN-y 653 $aIL-10 653 $aIntrathoracic route 700 1 $aAZEVEDO, A. L. S. 700 1 $aRODRIGUES, M. F. 700 1 $aMACHADO, R. P. 700 1 $aSOUZA, M. A. 700 1 $aMACHADO, M. A. 700 1 $aTEIXEIRA, H. C. 700 1 $aFERREIRA, A. P. 773 $tComparative Immunology, Microbiology and Infectious Discases$gv. 32, n. 6, p. 513-525, 2009.
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