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Registro Completo |
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Biblioteca(s): |
Embrapa Clima Temperado. |
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Data corrente: |
17/12/2021 |
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Data da última atualização: |
17/12/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
SILVA, D. T. da; SMANIOTTO, F. A.; COSTA, I. F.; BARANZELLI, J.; MULLER, A.; SOMACAL, S.; MONTEIRO, C. S.; VIZZOTTO, M.; RODRIGUES, E.; BARCIA, M. T.; EMANUELLI, T. |
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Afiliação: |
DARIANE TRIVISIOL DA SILVA; FRANCIELE ALINE SMANIOTTO; ISABELLA FERREIRA COSTA; JULIA BARANZELLI; ALINE MULLER; SABRINA SOMACAL; CAMILA SANT'ANNA MONTEIRO; MARCIA VIZZOTTO, CPACT; ELISEU RODRIGUES; MILENE TEIXEIRA BARCIA; TATIANA EMANUELLI. |
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Título: |
Natural deep eutectic solvent (NADES): A strategy to improve the bioavailability of blueberry phenolic compounds in a ready-to-use extract. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Food Chemistry, v. 364, 130370, Dec. 2021. |
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DOI: |
doi.org/10.1016/j.foodchem.2021.130370 |
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Idioma: |
Inglês |
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Conteúdo: |
This study investigated whether a ready-to-use extract obtained using a natural deep eutectic solvent (NADES) affects the pharmacokinetic profile of blueberry phenolic compounds compared to organic solvent (SORG)-extracted compounds. SORG extract was administered as an aqueous solution after solvent removal. Wistar rats received a single dose of crude extract of blueberry obtained using NADES (CE-NADES) or SORG (CE-SORG), followed by LC-DAD-MS/MS analysis of blood and cecal feces. Non-compartmental pharmacokinetic analysis revealed that CE-NADES increased the bioavailability of anthocyanins by 140% compared to CE-SORG. CE-NADES increased the stability of phenolic compounds during in vitro digestion by delaying gastric chyme neutralization. These results suggest that besides being an eco-friendly solvent for the extraction of phytochemicals, choline chloride:glycerol:citric acid-based NADES can be used as a ready-to-use vehicle for increasing oral absorption of bioactive compounds such as anthocyanins. |
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Palavras-Chave: |
Composto. |
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Thesagro: |
Extrato; Mirtilo. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/229347/1/Artigo-Natural-deep-eutectic-solvent.pdf
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Marc: |
LEADER 01878naa a2200289 a 4500
001 2138030
005 2021-12-17
008 2021 bl uuuu u00u1 u #d
024 7 $adoi.org/10.1016/j.foodchem.2021.130370$2DOI
100 1 $aSILVA, D. T. da
245 $aNatural deep eutectic solvent (NADES)$bA strategy to improve the bioavailability of blueberry phenolic compounds in a ready-to-use extract.$h[electronic resource]
260 $c2021
520 $aThis study investigated whether a ready-to-use extract obtained using a natural deep eutectic solvent (NADES) affects the pharmacokinetic profile of blueberry phenolic compounds compared to organic solvent (SORG)-extracted compounds. SORG extract was administered as an aqueous solution after solvent removal. Wistar rats received a single dose of crude extract of blueberry obtained using NADES (CE-NADES) or SORG (CE-SORG), followed by LC-DAD-MS/MS analysis of blood and cecal feces. Non-compartmental pharmacokinetic analysis revealed that CE-NADES increased the bioavailability of anthocyanins by 140% compared to CE-SORG. CE-NADES increased the stability of phenolic compounds during in vitro digestion by delaying gastric chyme neutralization. These results suggest that besides being an eco-friendly solvent for the extraction of phytochemicals, choline chloride:glycerol:citric acid-based NADES can be used as a ready-to-use vehicle for increasing oral absorption of bioactive compounds such as anthocyanins.
650 $aExtrato
650 $aMirtilo
653 $aComposto
700 1 $aSMANIOTTO, F. A.
700 1 $aCOSTA, I. F.
700 1 $aBARANZELLI, J.
700 1 $aMULLER, A.
700 1 $aSOMACAL, S.
700 1 $aMONTEIRO, C. S.
700 1 $aVIZZOTTO, M.
700 1 $aRODRIGUES, E.
700 1 $aBARCIA, M. T.
700 1 $aEMANUELLI, T.
773 $tFood Chemistry$gv. 364, 130370, Dec. 2021.
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Registro original: |
Embrapa Clima Temperado (CPACT) |
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Biblioteca |
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Origem |
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Registro |
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URL |
Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Amazônia Oriental. |
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Data corrente: |
18/01/2005 |
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Data da última atualização: |
19/08/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
Nacional - B |
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Autoria: |
KANASHIRO, M.; THOMPSON, I. S.; YARED, J. A. G.; LOVELESS, M. D.; COVENTRY, P.; MARTINS-DA-SILVA, R. C. V.; DEGEN, B.; AMARAL, W. |
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Afiliação: |
MILTON KANASHIRO, CPATU; Ian S. Thompson, DFID; JORGE ALBERTO GAZEL YARED, CPATU; Marilyn D. Loveless, College of Wooster / Visiting Scientist, Embrapa; Peter Coventry, DFID; REGINA CELIA VIANA MARTINS DA SILVA, CPATU; Bernd Degen, INRA; Weber Amaral, IPGRI. |
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Título: |
Improving conservation values of managed forests: the dendrogene project in the Brazilian Amazon. |
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Ano de publicação: |
2002 |
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Fonte/Imprenta: |
Unasylva, v. 53, n. 209, p. 25-33, 2002. |
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Descrição Física: |
il. |
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Idioma: |
Inglês |
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Palavras-Chave: |
Conservação de recurso; Manejo florestal. |
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Thesaurus NAL: |
Amazonia. |
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Categoria do assunto: |
K Ciência Florestal e Produtos de Origem Vegetal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/43069/1/5420.pdf
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Marc: |
LEADER 00684naa a2200241 a 4500
001 1405889
005 2020-08-19
008 2002 bl uuuu u00u1 u #d
100 1 $aKANASHIRO, M.
245 $aImproving conservation values of managed forests$bthe dendrogene project in the Brazilian Amazon.
260 $c2002
300 $cil.
650 $aAmazonia
653 $aConservação de recurso
653 $aManejo florestal
700 1 $aTHOMPSON, I. S.
700 1 $aYARED, J. A. G.
700 1 $aLOVELESS, M. D.
700 1 $aCOVENTRY, P.
700 1 $aMARTINS-DA-SILVA, R. C. V.
700 1 $aDEGEN, B.
700 1 $aAMARAL, W.
773 $tUnasylva$gv. 53, n. 209, p. 25-33, 2002.
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Registro original: |
Embrapa Amazônia Oriental (CPATU) |
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