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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
26/02/1996 |
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Data da última atualização: |
23/06/2023 |
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Autoria: |
ELLIS, J. A.; HAWK, D. A.; MILLS, K. W.; PRATT, D. L. |
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Título: |
Antigen specificity and activity of ovine antibodies induced by immunization with Corybebacterium Pseudotuberculosis culture filtrate. |
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Ano de publicação: |
1991 |
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Fonte/Imprenta: |
Veterinary Immunology and Immunopathology, v. 28, n. 3/4, p. 303-316, 1991. |
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DOI: |
https://doi.org/10.1016/0165-2427(91)90122-S |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Sheep were immunized three times with a vaccine composed of filtrate from a 36 h culture of Corynebacterium pseudotuberculosis and a block polymer adjuvant. Immunization resulted in the development of exotoxin-neutralizing antibody. This corresponded to the recognition of a 31.6 kDa protein on sequential immunoblots of ammonium sulfate-precipitated filtrate. In addition, sera from vaccinated sheep recognized at least eight bacterial cellular antigens on immunoblots of ether-extracted C. pseudotuberculosis, including bands of 12, 25.1, 31.6, 36.3, 39.8, 63.1, 70, 75 or 79.4 kDa. Sera from these sheep altered the colony growth characteristics of C. pseudotuberculosis in vitro. These results indicate that immunization with soluble C. pseudotuberculosis antigen preparations that have been used in toxoid vaccines induces antibody responses to numerous cellular antigens in addition to exotoxin and suggest that serologically mediated antibacterial effects could be an important component in the protection from disease that has been reported following immunization with C. pseudotuberculosis toxoids. |
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Thesagro: |
Corynebacterium Pseudotuberculosis; Doença; Linfadenite Caseosa; Ovino. |
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Thesaurus Nal: |
Bacterial antibodies; Bacterial vaccines; Biosynthesis; Disease control; Disease prevention; Enzyme-linked immunosorbent assay; Immunoblotting; Immunology; Molecular weight; Polyacrylamide gel electrophoresis; Sheep diseases. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02248naa a2200349 a 4500
001 1523339
005 2023-06-23
008 1991 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/0165-2427(91)90122-S$2DOI
100 1 $aELLIS, J. A.
245 $aAntigen specificity and activity of ovine antibodies induced by immunization with Corybebacterium Pseudotuberculosis culture filtrate.$h[electronic resource]
260 $c1991
520 $aAbstract: Sheep were immunized three times with a vaccine composed of filtrate from a 36 h culture of Corynebacterium pseudotuberculosis and a block polymer adjuvant. Immunization resulted in the development of exotoxin-neutralizing antibody. This corresponded to the recognition of a 31.6 kDa protein on sequential immunoblots of ammonium sulfate-precipitated filtrate. In addition, sera from vaccinated sheep recognized at least eight bacterial cellular antigens on immunoblots of ether-extracted C. pseudotuberculosis, including bands of 12, 25.1, 31.6, 36.3, 39.8, 63.1, 70, 75 or 79.4 kDa. Sera from these sheep altered the colony growth characteristics of C. pseudotuberculosis in vitro. These results indicate that immunization with soluble C. pseudotuberculosis antigen preparations that have been used in toxoid vaccines induces antibody responses to numerous cellular antigens in addition to exotoxin and suggest that serologically mediated antibacterial effects could be an important component in the protection from disease that has been reported following immunization with C. pseudotuberculosis toxoids.
650 $aBacterial antibodies
650 $aBacterial vaccines
650 $aBiosynthesis
650 $aDisease control
650 $aDisease prevention
650 $aEnzyme-linked immunosorbent assay
650 $aImmunoblotting
650 $aImmunology
650 $aMolecular weight
650 $aPolyacrylamide gel electrophoresis
650 $aSheep diseases
650 $aCorynebacterium Pseudotuberculosis
650 $aDoença
650 $aLinfadenite Caseosa
650 $aOvino
700 1 $aHAWK, D. A.
700 1 $aMILLS, K. W.
700 1 $aPRATT, D. L.
773 $tVeterinary Immunology and Immunopathology$gv. 28, n. 3/4, p. 303-316, 1991.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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