| |
|
|
 | Acesso ao texto completo restrito à biblioteca da Embrapa Meio Ambiente. Para informações adicionais entre em contato com cnpma.biblioteca@embrapa.br. |
|
Registro Completo |
|
Biblioteca(s): |
Embrapa Meio Ambiente. |
|
Data corrente: |
03/08/2017 |
|
Data da última atualização: |
23/10/2017 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Autoria: |
CLEMENTE, Z.; CASTRO, V. L. S. S. de; FRANQUI, L.; SILVA, C. A.; MARTINEZ, D. S. T. |
|
Afiliação: |
ZAIRA CLEMENTE, CNPEM; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; LIDIANE FRANQUI, CNPEM; CRISTIANE A SILVA, CNPEM; DIEGO STEFANI TEODORO MARTINEZ, CNPEM. |
|
Título: |
Nanotoxicity of graphene oxide: assessing the influence of oxidation debris in the presence of humic acid. |
|
Ano de publicação: |
2017 |
|
Fonte/Imprenta: |
Environmental Pollution, v. 225, p. 118-128, 2017. |
|
DOI: |
http://dx.doi.org/10.1016/j.envpol.2017.03.033 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Abstract: This study sought to evaluate the toxicological effects of graphene oxide (GO) through tests with Danio rerio (zebrafish) embryos, considering the influence of the base washing treatment and the interaction with natural organic matter (i.e., humic acid, HA). A commercial sample of GO was refluxed with NaOH to remove oxidation debris (OD) byproducts, which resulted in a base washed GO sample (bw-GO). This process decreased the total oxygenated groups in bw-GO and its stability in water compared to GO. When tested in the presence of HA, both GO and bw-GO stabilities were enhanced in water. Although the embryo exposure showed no acute toxicity or malformation, the larvae exposed to GO showed a reduction in their overall length and acetylcholinesterase activity. In the presence of HA, GO also inhibited acid phosphatase activity. Our findings indicate a mitigation of material toxicity after OD removal. The difference in the biological effects may be related to the materials? bioavailability and biophysicochemical interactions. This study reports for the first time the critical influence of OD on the GO material biological reactivity and HA interaction, providing new data for nanomaterial environmental risk assessment and sustainable nanotechnology. |
|
Palavras-Chave: |
Biomarker; Nanoecotoxicology; Zebrafish. |
|
Thesagro: |
Composto químico; Matéria orgânica; Peixe de água doce; Toxidez. |
|
Thesaurus Nal: |
embryotoxicity; nanotechnology. |
|
Categoria do assunto: |
-- |
|
Marc: |
LEADER 02151naa a2200289 a 4500
001 2073578
005 2017-10-23
008 2017 bl uuuu u00u1 u #d
024 7 $ahttp://dx.doi.org/10.1016/j.envpol.2017.03.033$2DOI
100 1 $aCLEMENTE, Z.
245 $aNanotoxicity of graphene oxide$bassessing the influence of oxidation debris in the presence of humic acid.$h[electronic resource]
260 $c2017
520 $aAbstract: This study sought to evaluate the toxicological effects of graphene oxide (GO) through tests with Danio rerio (zebrafish) embryos, considering the influence of the base washing treatment and the interaction with natural organic matter (i.e., humic acid, HA). A commercial sample of GO was refluxed with NaOH to remove oxidation debris (OD) byproducts, which resulted in a base washed GO sample (bw-GO). This process decreased the total oxygenated groups in bw-GO and its stability in water compared to GO. When tested in the presence of HA, both GO and bw-GO stabilities were enhanced in water. Although the embryo exposure showed no acute toxicity or malformation, the larvae exposed to GO showed a reduction in their overall length and acetylcholinesterase activity. In the presence of HA, GO also inhibited acid phosphatase activity. Our findings indicate a mitigation of material toxicity after OD removal. The difference in the biological effects may be related to the materials? bioavailability and biophysicochemical interactions. This study reports for the first time the critical influence of OD on the GO material biological reactivity and HA interaction, providing new data for nanomaterial environmental risk assessment and sustainable nanotechnology.
650 $aembryotoxicity
650 $ananotechnology
650 $aComposto químico
650 $aMatéria orgânica
650 $aPeixe de água doce
650 $aToxidez
653 $aBiomarker
653 $aNanoecotoxicology
653 $aZebrafish
700 1 $aCASTRO, V. L. S. S. de
700 1 $aFRANQUI, L.
700 1 $aSILVA, C. A.
700 1 $aMARTINEZ, D. S. T.
773 $tEnvironmental Pollution$gv. 225, p. 118-128, 2017.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Meio Ambiente (CNPMA) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
|
|
|
| Registros recuperados : 441 | |
| Registros recuperados : 441 | |
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
