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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
12/09/1996 |
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Data da última atualização: |
12/09/1996 |
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Autoria: |
LANUSSE, C. E.; PRICHARD, R. K. |
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Título: |
Relationship between pharmacological properties and clinical efficacy of ruminant anthelmintics. |
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Ano de publicação: |
1993 |
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Fonte/Imprenta: |
Veterinary Parasitology, v.49, n.2-4, p.123-158, 1993. |
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Idioma: |
Inglês |
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Conteúdo: |
The purpose of this review article is to establish a relationship between pharmacological properties and clinical efficacy of the most widely used broad-spectrum veterinary anthelmintics. The impact of drug pharmacokinetics/pharmacodynamics on anthelmintic efficacy and resistance is discussed. We review the clinical pharmacokinetics of the currently available anthelmintics used in livestock-imidazothiazoles, tetrahydropyrimidines, benzimidazoles/pro-benzimidazoles, salicylanilides (closantel) and a avermectin-type compounds. Understanding the pharmacokinetic and metabolic behaviour of broad-spectrum anthelmintics in the host, and factors modulating that behaviour, is highly iimportant for maximizing anthelmintic utility and efficacy. |
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Palavras-Chave: |
Anthelmintic control; Controle antihelmintico; Ruminant. |
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Thesagro: |
Parasitologia; Ruminante. |
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Thesaurus Nal: |
parasitology. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01338naa a2200205 a 4500
001 1517240
005 1996-09-12
008 1993 bl uuuu u00u1 u #d
100 1 $aLANUSSE, C. E.
245 $aRelationship between pharmacological properties and clinical efficacy of ruminant anthelmintics.
260 $c1993
520 $aThe purpose of this review article is to establish a relationship between pharmacological properties and clinical efficacy of the most widely used broad-spectrum veterinary anthelmintics. The impact of drug pharmacokinetics/pharmacodynamics on anthelmintic efficacy and resistance is discussed. We review the clinical pharmacokinetics of the currently available anthelmintics used in livestock-imidazothiazoles, tetrahydropyrimidines, benzimidazoles/pro-benzimidazoles, salicylanilides (closantel) and a avermectin-type compounds. Understanding the pharmacokinetic and metabolic behaviour of broad-spectrum anthelmintics in the host, and factors modulating that behaviour, is highly iimportant for maximizing anthelmintic utility and efficacy.
650 $aparasitology
650 $aParasitologia
650 $aRuminante
653 $aAnthelmintic control
653 $aControle antihelmintico
653 $aRuminant
700 1 $aPRICHARD, R. K.
773 $tVeterinary Parasitology$gv.49, n.2-4, p.123-158, 1993.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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