02827naa a2200397 a 450000100080000000500110000800800410001902400270006010000210008724500900010826000090019852016090020765000160181665000150183265000270184765000350187465000160190965000180192565300320194365300390197565300400201465300450205465300210209965300360212070000220215670000160217870000190219470000170221370000230223070000310225370000200228470000210230470000220232570000260234777300560237319984062022-11-16       2014    bl uuuu     u00u1 u    #d7 a10.1111/age.122102DOI1 aSOMAVILLA, A. L.  aA genome-wide scan for selection signatures in Nellore cattle.h[electronic resource]  c2014  aBrazilian Nellore cattle (Bos indicus) have been selected for growth traits for over more than four decades. In recent years, reproductive and meat quality traits have become more important because of increasing consumption, exports and consumer demand. The identification of genome regions altered by artificial selection can potentially permit a better understanding of the biology of specific phenotypes that are useful for the development of tools designed to increase selection efficiency. Therefore, the aims of this study were to detect evidence of recent selection signatures in Nellore cattle using extended haplotype homozygosity methodology and BovineHD marker genotypes (&gt777 000 single nucleotide polymorphisms) as well as to identify corresponding genes underlying these signals. Thirty-one significant regions (P &lt 0.0001) of possible recent selection signatures were detected, and 19 of these overlapped quantitative trait loci related to reproductive traits, growth, feed efficiency, meat quality, fatty acid profiles and immunity. In addition, 545 genes were identified in regions harboring selection signatures. Within this group, 58 genes were associated with growth, muscle and adipose tissue metabolism, reproductive traits or the immune system. Using relative extended haplotype homozygosity to analyze high-density single nucleotide polymorphism marker data allowed for the identification of regions potentially under artificial selection pressure in the Nellore genome, which might be used to better understand autozygosity and the effects of selection on the Nellore genome.  aBeef cattle  aGenotyping  aLinkage disequilibrium  aSingle nucleotide polymorphism  aBos Indicus  aGado de corte  aDesequilíbrio de ligação  aHomozigose do haplótipo estendido  aPolimorfismo de nucleotídeo único  aRelative extended haplotype homozygosity  aSingle nucleotid  aSingle nucleotide polymorphisms1 aSONSTEGARD, T. S.1 aHIGA, R. H.1 aROSA, A. do N.1 aSIQUEIRA, F.1 aSILVA, L. O. C. da1 aTORRES JUNIOR, R. A. de A.1 aCOUTINHO, L. L.1 aMUDADU, M. de A.1 aALENCAR, M. M. de1 aREGITANO, L. C. de A.  tAnimal Geneticsgv. 45, n. 6, p. 771-781, dec. 2014