02808naa a2200373 a 450000100080000000500110000800800410001902400370006010000230009724501140012026000090023452017350024365000180197865000220199665000100201865000120202865000210204065000250206165000150208665000100210165000110211165300300212265300120215265300310216465300140219570000210220970000210223070000350225170000170228670000190230370000190232270000240234177300690236519713002015-03-18       2013    bl uuuu     u00u1 u    #d7 a0.1016/j.vetpar.2013.04.0142DOI1 aOLIVEIRA, L. M. B.  aEffects of Mimosa tenuiflora on larval establishment of Haemonchus contortus in sheep.h[electronic resource]  c2013  aAbstract: Anthelmintic resistance has limited the ability to control the gastrointestinal nematodes of small ruminants and has therefore awakened an interest in the study of tanniferous plants as a source of anthelmintics. This study was carried out to evaluate the effect of Mimosa tenuiflora intake, a tanniferous plant that is fed to small ruminants in northeastern Brazil, on the larval establishment of Haemonchus contortus in sheep. In this experiment, 18 nematode-free sheep were divided into three groups (n=6) according to live weight. Group 1 was fed M. tenuiflora leaves; Group 2 was fed M. tenuiflora stems; Group 3 served as the control group and was fed Cynodon dactylon, a plant with low levels of tannins. The animals consumed the plants for 13 days (Day -7 to Day 5). On Day 0, the sheep were experimentally infected with 4500 third-stage H. contortus each. Five days after infection (Day 5), the sheep were slaughtered to count the worm burden and perform a histological analysis of the abomasum. The daily plant intake and the live weight gain of the animals were recorded. The groups that ingested M. tenuiflora leaves and stems consumed less dry matter than did those that ingested C. dactylon (P&lt0.05). The consumption of M. tenuiflora leaves did not reduce the L3 establishment of H. contortus compared to the control (P&gt0.05). The intake of M. tenuiflora stems tended toward decreasing larval establishment, but the reduction was not significant (P&gt0.05). No significant differences were observed in the mucosal cellular response and live weight gain among the groups. These data demonstrated that, with the protocol used, M. tenuiflora has no effect on larval establishment of H. contortus in sheep.  aAnthelmintics  aMimosa tenuiflora  aSheep  aTannins  aAnti-helmíntico  aHaemonchus contortus  aNematóide  aOvino  aTanino  aGastrointestinal diseases  aIn vivo  aNematódeo gastrintestinal  aNematodes1 aMACEDO, I. T. F.1 aVIEIRA, L. da S.1 aCAMURÇA-VASCONCELOS, A. L. F.1 aTOMÉ, A. R.1 aSAMPAIO, R. A.1 aLOUVANDINI, H.1 aBEVILAQUA, C. M. L.  tVeterinary Parasitologygv. 196, n. 3/4, p. 341-346, Sept. 2013.