02391nam a2200157 a 450000100080000000500110000800800410001910000150006024500940007526002330016930000120040252017580041465000350217265000130220770000130222019513002013-02-26       2012    bl uuuu     u00u1 u    #d1 aCHIARI, L.  aGene discovery by functional genomics approaches in forage plants.h[electronic resource]  aIn: JORNADAS LATINOAMERICANAS DE RECURSOS GENÉTICOS, MEJORAMIENTO Y BIOTECNOLOGÍA DE ESPECIES FORRAJERAS, 2012, Buenos Aires. [Anales...]. Junin : Universidad Nacional del Noroeste de la Provincia de Buenos Aires. UNNOBAc2012  ap.42-47  aThe knowledge about the nature and content of genetic information, as well as the available technologies for DNA high-throughput sequencing (Next Generation Sequence - NGS) evolved rapidly in the last two decades. This enabled the accumulation of a large quantity of information about the nucleotide sequences of various genomes (microorganisms, plants and animals) and much of this information is available in public data banks. However, the data obtained in the sequencing projects did not contribute as expected to the understanding of the role of the genes in the function of the organisms, since the genome is a virtually static element, whereas its products, messenger RNAs and proteins, have a dynamic character which is characterized by continuous changes in response to internal and external stimuli (Greenbaum et al., 2001). In this context, the Functional Genomics emerged with the objective of knowing the individual functions of the genes and its products, RNAs (transcriptome) and proteins (proteome). This new area of research uses analytical techniques that allow to evaluate the patterns of genic and proteic expressions in cells and tissues, a basic prerequisite to understand how these macromolecules interact dynamically to produce complex organisms which are able to adapt to environmental influences and to specific metabolic-physiological situations. The results of research in Functional Genomics, especially those involving genetically different individuals or those subjected to contrasting conditions, have permitted a faster and more accurate understanding of gene-phenotype relationships, and dissect the genotype-environment interactions that cause significant changes in the phenotype of individuals (FURLAN et al., 2007).  aMelhoramento Genético Vegetal  aPastagem1 aJANK, L.