01274naa a2200241 a 450000100080000000500110000800800410001902400320006010000240009224501210011626000090023752005210024665000210076765000160078865300250080465300210082970000240085070000180087470000230089270000170091570000210093277300790095319372322017-09-21       2012    bl uuuu     u00u1 u    #d7 a10.1002/ejoc.2012007572DOI1 aARAUJO, F. D. DA S.  aEpicolactonebnatural product isolated from the sugarcane endophytic fungus Epicoccum nigrum.h[electronic resource]  c2012  aThe endophytic fungusEpicoccum nigrumwas isolated from sugarcane and the bioguided fractionation of the ethyl acet-ate extract led to the isolation of epicolactone, mellein, and 4,5-dimethylresorcinol. Characterization of epicolactone by MS, NMR and X-ray crystallography revealed a new natural product with an unusual carbon skeleton. The production of this secondary metabolite decreased in mutants of Epi-coccum nigrumtransformed byAgrobacterium tumefaciens. Additionally, these mutants produced 4-hydroxymellein.  aEpicoccum nigrum  amutagenesis  aBioorganic chemistry  aNatural products1 aFAVARO, L. C. de L.1 aARAUJO, L. W.1 aOLIVEIRA, F. L. DE1 aAPARICIO, R.1 aMARSAIOLI, A. J.  tEuropean Journal of Organic Chemistrygv. 2012, n. 27, p. 5225?5230, 2012.