01996naa a2200301 a 450000100080000000500110000800800410001910000240006024501170008426000090020152011410021065000190135165000200137065000160139065000150140665000170142165000240143865000140146265000240147665000160150065000120151665300230152865300140155170000190156570000190158470000200160377300710162319332192015-10-16       2012    bl uuuu     u00u1 u    #d1 aANDREU-SÁNCHEZ, O.  aAcute toxicity and bioconcentration of fungicide tebuconazole in zebrafish (Danio rerio).h[electronic resource]  c2012  aThis research work investigated the bioconcentration of tebuconazole [(+-)-?-[2-(4-chlorophenyl) ethyl]-?-(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol] fungicide in zebrafish (Danio rerio) under laboratory conditions and a first-order kinetic pesticide dissipation in the water. The concentrations of tebuconazole fitted to an equivalent nonlinear kinetic type model which allowed the calculation of the following parameters: bioconcentration factor (38.80 L kg-1), time to reach maximum fish concentration (6 days), maximum concentration in fish (0.0075 ?g mg-1), half-life in fish (24 days) and time needed for the fish to eliminate 95% of the maximum concentration (105 days). These calculations permitted the establishment of theoretical reference limit values for human consumption of fish and the establishment of safe limits for the water pesticide concentration. The data would also be useful in safe strategies associated with fishery activities that are conducted in aquatic regions close to crops using tebuconazole. The information will contribute to enlarge the tebuconazole toxicokinetics database of aquatic organisms.  aAcute toxicity  aBioaccumulation  aDanio rerio  aFungicides  aTebuconazole  aTriazole fungicides  aFungicida  aPeixe de água doce  aToxicologia  aToxidez  aPirycularia orizae  aRice crop1 aPARAIBA, L. C.1 aJONSSON, C. M.1 aCARRASCO, J. M.  tEnvironmental Toxicology, New Yorkgv. 27, n. 2, p. 109-116, 2012.