01450naa a2200205 a 450000100080000000500110000800800410001902400360006010000220009624500710011826000090018952008720019865000160107065000150108665000150110165300200111670000260113670000180116277300640118019050952011-11-08       2011    bl uuuu     u00u1 u    #d7 a10.2174/1872312117969050532DOI1 aFREITAS-SILVA, O.  aTracing fungi secondary metabolites in Brazil nuts using LC-MS/MS.  c2011  aThis screening aimed to evaluate quantitatively the occurrence of fungal metabolites in Brazil nuts. Nuts were collected from Agroforest production areas in Amazon basin region. A total of 235 mycotoxins (including the most prominent ones) was screened by a multi-mycotoxin method based on HPLC-MS/MS. The recovery of metabolites by the method was between 56 and 136%. Fifteen mycotoxins were detected and quantified, in at least one sample; namely, aflatoxins (AFB1, AFB2, AFG1, and AFM1), sterigmatocystin, methyl-sterigmatocystin, kojic acid, citrinin, cyclosporin A, cyclosporin C, cyclosporin D, cyclosporin H, rugulosin, alternariol-methylether and emodin. This is the first study dealing with the detection of the latter nine metabolites in Brazil nuts. Alternariol-methylether (from 0.75 to 3.2 ?g/kg) was the only metabolite detected in all analyzed samples.  aAspergillus  aAflatoxina  aMicotoxina  aAspergillus spp1 aSOUZA, M. de L. M. de1 aVENÂNCIO, A.  tDrug Metabolism Lettersgv. 5, n. 3, p. 150-155, Aug. 2011.