01862naa a2200289 a 450000100080000000500110000800800410001902400390006010000220009924501250012126000090024652010120025565000110126765000170127865300110129565300190130665300090132565300350133470000210136970000190139070000230140970000200143270000200145270000200147270000260149277300540151819003462023-02-17       2012    bl uuuu     u00u1 u    #d7 a10.1016/j.meatsci.2011.08.0052DOI1 aNICIURA, S. C. M.  aPolymorphism and parent-of-origin effects on gene expression of CAST, leptin and DGAT1 in cattle.h[electronic resource]  c2012  aThis study aimed to investigate differential allele expression (DAE) and polymorphism and parent-of-origin effects on expression of genes related to beef traits. CAST, related to meat tenderness, and DGAT1 and leptin, related to fat deposition, were evaluated. In bovine fetal tissues CAST was expressed twice as much (Pb0.05) in muscle of homozygous GG than in heterozygous AG. Leptin was expressed about one-tenth as much (Pb0.05) in heterozygous TpCm (allele T of paternal origin and allele C of maternal origin) than in homozygous CC. No DAE was observed. The evidence of polymorphism effect on expression of CAST and parent-of-origin effect on leptin contributes to a better understanding of events controlling the expression of genes of economic interest in cattle. Furthermore, if the parent-of-origin effects observed in fetal tissues are confirmed in adult tissues and associated to phenotypic variation, this parental origin criterion may be considered in marker-assisted selection of beef traits.  aleptin  ameat quality  aBovine  aCarcass traits  aCAST  aDifferential allele expression1 aIBELLI, A. M. G.1 aGOUVEIA, G. V.1 aGOMBRONI, J. G. G.1 aROCHA, M. I. P.1 aSOUZA, M. M. de1 aMELLO, S. S. de1 aREGITANO, L. C. de A.  tMeat Sciencegv. 90, n. 2, p. 507-510, feb. 2012.