01328naa a2200241 a 450000100080000000500110000800800410001910000120006024500730007226000090014552006780015465000150083265000130084765000140086065000160087465300250089065300230091565300260093870000180096470000140098270000160099677300740101217893651996-07-12       1977    bl ---       0--  u    #d1 aDAS, M.  aMetabolic correlates of immune dysfunction in malnourished children.  c1977  aMononuclear cells of malnourished children contain diminished activity of phosphoglycerate kinase and pyruvate kinase (PK). The PK activily of these cells correlates well with the percentage of circulating thymus-derived Iymphoytes (T-cells). Phytothemagglutinin causes an immediate increase in PK activity of mononuclear cells of malnourished patients. The correlation of PK activity with T-ceIls and lhe response of PK activity to phytohemagglutin are in distinct contrast to observed perturbations of neonatal mononuclear ceIl metabolism. The relationship of the metabolic alterations to the pathophysiology of the immune system in malnutrition has not yet been defined.  ametabolism  aCriança  aImunidade  aMetabolismo  aDeficiencia organica  aImmune dysfunction  aMalnourished children1 aSTIEHM, E. R.1 aBORUT, T.1 aFEIG, S. A.  tAmerican Journal of Clinical Nutritiongv.30, p.1949-1952, Dec. 1977.