01294nam a2200277 a 450000100080000000500110000800800410001910000180006024501360007826001330021430000190034750000150036652003610038165000230074265000240076565000140078965000160080365300230081965300140084265300190085665300240087565300480089965300370094770000180098470000140100216611992020-01-15       2009    bl uuuu     u00u1 u    #d1 aCASTRO, A. de  aA mathematical model of cell dynamics to simulate viral mutations and its influence on the memory reservoir.h[electronic resource]  aIn: THE AMERICAN MEDICAL INFORMATION ASSOCIATION ANNUAL SYMPOSIUM, 2009, San Francisco. Proceedings... San Francisco: AMIAc2009  cNão paginado.  aAMIA 2009.  aIn this paper we use virtual samples of mammals and a dynamical modeling proposed by one of the authors in a previous study to study the behavior of immune memory agains antigenic mutation. Our results in silico suggest that the sustainability of the immunizations is nos a stochastic process, what contradicts the current opinion (Tarlinton et. al., 2008)  aImmunologic memory  aMathematical models  aMutação  aSimulação  aDynamical modeling  aIn silico  aMemória imune  aModelagem dinâmica  aModelo matemático de dinâmica de células  aSimulação de mutações virais1 aFRONZA, C. F.1 aALVES, D.