03028naa a2200337 a 450000100080000000500110000800800410001910000160006024502170007626000090029352020500030265000160235265000170236865000120238565000120239765000140240965000140242365000170243765000100245465000090246465000160247365000100248965000120249965000240251165000110253570000150254670000190256170000170258070000130259777300800261015337672023-07-11       1979    bl uuuu     u00u1 u    #d1 aGRIZARD, J.  aVariations des teneurs sanguines en acides aminés libres, urée et glucose chez la brebis en fin de gestation et début de lactation. Influence de l?état nutritionnel en fin de gestation.h[electronic resource]  c1979  a[Glucose, urea, amino acids in the blood of ewes during pregnancy and lactation. Effect of nutritional state during late pregnancy]. Abstract: A factorial experiment using 28 Limousine ewes (table 1) was carried out to study protein metabolism during pregnancy and lactation. The experimental treatments included two levels of energy intake during 7 weeks prepartum (high : H ; low : B) (table 2) and two states of body reserves at 8 weeks prepartum (fat : G ; lean : M). The animals bore or were suckling either twins (D) or singles (S). Preprandial and postprandial jugular blood samples were taken at 38, 24 and 10 days prepartum and at 5, 13, 26 and 40 days postpartum. Blood glucose, urea and free amino acids were recorded. During pregnancy. Reducing dietary energy supply resulted in a large decrease of lamb birthweight (-0.8 kg) and a diminution of the levels of glucose (fig. 1), some non-essential (alanine, citrulline) and some essential (tyrosine, phenylalanine, threonine, valine, leucine) free amino acids (fig. 3) in the blood of ewes ; blood urea increased (fig. 2). Reducing body reserves caused a small drop in lamb birthweight (―0.3 kg) and an increment of glucose (fig. 1) and free methionine (fig. 3) in the blood. During the last 2 weeks of pregnancy, postprandial blood glucose level rose (fig. 1). During lactation. During the first 2 weeks of lactation, the amino acid requirements for milk protein synthesis were higher than amino acid supply by the digestive tract (fig. 5). At 1 week postpartum, ewes showed very high blood levels of most ot the essential free amino acids, free proline and free glycine (fig. 4). Some of the essential free amino acids (valine. leucine, phenylalanine, lysine, histidine) then decreased. Reducing body reserves resulted in an increment of most of the essential free amino acids in the blood. Blood levels of some of these amino acids seemed to be related to blood free methionine (table 5). Reducing the energy supply of the diet during late pregnancy increased blood glucose.  aAmino acids  aBiochemistry  aFemales  aGlucose  aLactation  aPregnancy  aReproduction  aSheep  aUrea  aBioquímica  aOvino  aPrenhez  aReprodução Animal  aSangue1 aTISSER, M.1 aCHAMPREDON, C.1 aPRUGNAUD, J.1 aPION, R.  tAnnales de Biologie Animale, Biochimie, Biophysiquegv. 19, p. 55-71, 1979.