01562nam a2200253 a 450000100080000000500110000800800410001910000180006024500950007826001790017352007630035265000200111565000130113565000120114865000100116065000140117065000340118465000100121865000200122865300080124870000170125670000160127370000190128915333942025-01-30       2006    bl uuuu     u00u1 u    #d1 aMAN, W. Y. N.  aGenetic conseguences of selecting on PrP genotypes on terminal sire and hill sheep breeds.  aIn: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 8., 2006, Belo Horizonte, MG. Proceedings... Belo Horizonte: Instituto Prociência, 2006. 4 f. 1 CD-ROM.c2006  aThe current study aims to assess the impact of various PrP selection strategies on PrP allele frequencies, inbreeding and genetic gain in performance traits in terminal sire and hill sheep populations typical of those participating in sire referencing schemes. When PrP selection was targeted against VRQ genotypes only and the VRQ allele frequency was 30% or less, there was minimal impact on genetic gain and inbreeding. However, genetic gain was affected with selection in favour of the ARR allele when the frequency of this allele was below 60%. In general, inbreeding was unaffected by PrP selection as this selection was counter-balanced by a weaker selection on the performance trait when compared with the scenario when there was no selection on PrP.  aAnimal genetics  aGenotype  aScrapie  aSheep  aGenótipo  aMelhoramento Genético Animal  aOvino  aSistema Nervoso  aPrP1 aLEWIS, R. M.1 aBOULTON, K.1 aVILLANUEVA, B.