03280naa a2200277 a 450000100080000000500110000800800410001902400590006010000190011924500520013826000090019052024950019965000140269465000120270865000280272065000120274865000180276070000180277870000160279670000150281270000250282770000170285270000210286970000160289077300960290615304242016-10-03       2003    bl uuuu     u00u1 u    #d7 ahttp://dx.doi.org/10.1590/S0100-736X20030004000062DOI1 aCOLODEL, E. M.  aEnterotoxemia em caprinos no Rio Grande do Sul.  c2003  aSão descritos surtos de enterotoxemia em caprinos em cinco propriedades no Estado do Rio Grande do Sul. Os animais afetados eram, normalmente, encontrados mortos ou aprsentavam evolução aguda de 2 a 3 horas com acentuada depressão, cólicas abdominais e diarréia profusa com fibrina. Em duas propriedades relataram-se casos com a evolução de até 12 horas. Em treze animais necropsiados observaram-se aumento de líquidos nas cavidades abdominal, torácica e pericárdica, congestão e hiperemia da serosa e mucosa do intestino, conteúdo do cólon líquido com fibrina além de hemorragias de serosa e fibrina. Em um animal constatou-se microangiopatia cerebral caracterizada por acúmulo de material homogêneo e eosinofilico no espaço perivascular. No conteúdo intestinal, colônias com bastonetes morfológica e bioquimicamente sugestivos de Clostridium perfringens foram caracterizadas no estudo bacteriológico. A soroneutralização em camundongos com conteúdo intestinal dos animais afetados, revelou a presença da toxina épsilon. Estes acahdos evidenciam a enterotoxemia como doença de importância para a criação de caprinos no Rio Grande do Sul.  [Caprine enterotoxaemia in Rio Grande do Sul, Brazil].  Five outbreaks of caprine enterotoxaemia in Rio Grande do Sul, Brazil, were studied. The animals were found dead or had a clinical course that usually lasted 2-3 hours. From two farms a clinical manifestation period of 12 hours was reported. Clinical signs were characterized by depression, marked abdominal discomfort, profuse watery diarrhea with fibrin clots, and death. Thirteen necropsies were performed and hydropericardium, hydrothorax and hydroperitoneum were commonly found. The mucosa and serosa of the colon were congested, and its contents was watery with multiple fibrin clots. Serosal hemorrhages and fibrin clots in the gallbladder were also seen. Fibrinous colitis and thyphilitis were the most frequent histological changes. Cerebral microangiopathy was observed in one case, which was characterized by acute perivascular proteinaceous edema around arterioles of the nucleus caudatus and thalamus. Large numbers of Gram-positive rods, often in clumps and with morphology consistent with Clostridium perfringens, were seen in intestinal smears. The intestinal contents of six goats were positive for epsilon toxin by mouse neutralization test. These findings suggest that enterotoxaemia is an important disease of goat flocks in southern Brazil.  aBactéria  aCaprino  aClostridium Perfringens  aDoença  aEnterotoxemia1 aDRIEMEIER, D.1 aSCHMITZ, M.1 aGERMER, M.1 aNASCIMENTO, R. A. P.1 aASSIS, R. A.1 aLOBATO, F. C. F.1 aUZAL, F. A.  tPesquisa Veterinária Brasileira, Rio de Janeirogv. 23, n. 4, p. 173-178, out./dez., 2003.