01830naa a2200253 a 450000100080000000500110000800800410001902400590006010000140011924501390013326000090027252010290028165000240131065000140133465000120134865000190136065000170137965000100139665300280140670000130143470000140144770000180146177300970147915294352026-04-07       2003    bl uuuu     u00u1 u    #d7 ahttp://dx.doi.org/10.1590/S0102-093520030002000152DOI1 aPOETA, P.  aResposta imunitária à vacinação conjuntiva com a estirpe Rev.1 de Brucella melitensis em ovinos e caprinos.h[electronic resource]  c2003  aSerological response of sheep and goats to conjunctival Brucella melitensis Rev.1 vaccine. The live B. melitensis Rev.1 strain is considered the best vaccine available for the prophylaxis of brucellosis in small ruminants, especially when used at the standard dose by the conjunctival route. In the present study a 1´ 109 CFU dose for both sheep and goats conjunctivally vaccinated was tested to evaluate the duration of serological responses. Conjunctival vaccination with Rev. 1 performed in adult animals induced a rapid rise in serological titres as measured by Rose Bengal Plate Test (RBPT), Complement Fixation Test (CF) and Modified Rose Bengal Plate Test (MRBPT). Titres then decreased and became negative in most animals by four months after vaccination (except MRBPT). The goats responded better to the vaccination than the sheep as one month after vaccination 100% of the goats revealed positive results to RB and RBM and 93.4% to FC test. The RBM was the one that detected more positive animals along the study.  aBrucella melitensis  aBrucelose  aCaprino  aDoença Animal  aImunização  aOvino  aVacinação conjuntival1 aNETO, F.1 aCOSTA, D.1 aRODRIGUES, J.  tArquivo Brasileiro de Medicina Veterinária e Zootecniagv. 55, n. 2, p. 220-222, abr. 2003.