01953naa a2200289 a 450000100080000000500110000800800410001902400500006010000170011024501640012726000090029152010650030065000210136565000200138665000270140665000120143365000120144565000190145765000140147665000150149065000190150565000190152465000170154365000140156070000180157477300710159215290602023-08-25       1974    bl uuuu     u00u1 u    #d7 ahttps://doi.org/10.1093/jmedent/11.3.3162DOI1 aJONES, R. H.  aOral infection of culicoides variipennis with bluetongue virusbdevelopment of susceptible and resistant lines from a colony population.h[electronic resource]  c1974  aAbstrnct: Four Jines of Culicoides vnriipennis (Coquillett), 3 susceptible and I resistant to oral infeclion with bluetongue vírus, were developed lhrough a genelic selection program of selected matings from a parent colony (SONORA strain, 000 line) with an intermediate susceptibility rate of 30%. Three of these 4 lines had mean infection rales of 92, 63, and 2% for a single infective blood meal for their 13, 27, and 15 generations of colony maintenance; data froro 2 repeated infective blood meals indicated that the 2 susceptible lines had susceptibility rates of 100% and that the resistant line was highly resistant. The data indica te that at least 2 genetic mechanisms govemed susceptibi1ity to oral infection with lhe virus; the 1st segregated rapidJy and appeared to be single gene contraI with lhe domi- nant aIlele for resistance; a 2nd mechanism controIled the threshold ofresponse. Our information suggests that an arbovirus disease might be tontroIled by Iowering the vector capac~y of a vector species without controIling the species itself.  aBluetongue virus  aCeratopogonidae  aCulicoides variipennis  aEcology  aFemales  aMouth diseases  aOrbivirus  aReoviridae  aSheep diseases  aDoença Animal  aResistência  aVirologia1 aFOSTER, N. M.  tJournal of Medical Entomologygv. 11, n. 3, p. 316-323, Jul. 1974.