02227naa a2200397 a 450000100080000000500110000800800410001902400380006010000160009824502180011426000090033252010120034165000180135365000200137165000200139165000230141165000170143465000180145165000170146965000190148665000210150565000140152665300140154065300300155470000180158470000160160270000180161870000150163670000180165170000210166970000200169070000170171070000180172770000190174577300650176415238742023-07-24       1995    bl uuuu     u00u1 u    #d7 a10.1016/0304-4017(95)00806-22DOI1 aWOOD, I. B.  aWorld Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) second edition of guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine, ovine, caprine).h[electronic resource]  c1995  aAbstract: The first edition of the W.A.A.V.P. anthelmintic guidelines for ruminants was published in 1982. Since then improved parasitological procedures have been developed, new therapeutic and prophylactic products have appeared requiring different test methods, and registration authorities are requesting more detailed record keeping and data validation. This second edition addresses these developments and fulfills the original goal of publishing guidelines for high quality, scientifically valid testing standards for trials that would be accepted as proof of efficacy by registration authorities regardless of country of origin. This second edition includes updated guidance on standard parasitological procedures, dose titration, dose confirmation and clinical trials, and provides guidelines for evaluating products for efficacy against anthelmintic resistant parasites, persistence of activity and prophylactic activity. Tests for efficacy against nematodes, trematodes and cestodes are included.  aAnthelmintics  aCattle diseases  aDisease control  aDisease prevention  aDrug therapy  aHelminthiasis  aPharmacology  aSheep diseases  aAnti-Helmíntico  aRuminante  aAvaliacao  aNematodeo gastrintestinal1 aAMARAL, N. K.1 aBAIRDEN, K.1 aDUNCAN, J. L.1 aKASSAI, T.1 aMALONE, J. B.1 aPANKAVICH, J. A.1 aREINECKE, R. K.1 aSLOCOMBE, O.1 aTAYLOR, S. M.1 aVERCRUYSSE, J.  tVeterinary Parasitologygv. 58, n. 3, p. 181-213, Jun. 1995.