01606naa a2200277 a 450000100080000000500110000800800410001902400320006010000210009224500820011326000090019552008800020465000190108465000100110365000130111365000180112665000150114465000150115965000170117465000100119165000150120165000100121665000170122665300190124377300660126215237682023-06-20       1978    bl uuuu     u00u1 u    #d7 a10.1677/joe.0.0790131.2DOI1 aFULKERSON, W. J.  aSynchronous episodic release of cortisol in the sheep.h[electronic resource]  c1978  aThe activity of the adrenal gland is believed to be governed by the secretion of corticotrophin (ACTH) in a positive stimulus/negative feedback equilibrium. There is increasing evidence that in man, the secretion of corticosteroids never actually reaches a steady-state condition and that the circadian rhythm displayed by these hormones in the circulation is therefore the result of a number of secretory episodes over a 24 h period (Hellman, Nakada, Curti, Weitzman, Kream, Roffwarg, Ellman, Fukushima & Gallagher, 1970; Weitzman, Fukushima, Nogeire, Roffwarg, Gallagher & Hellman, 1971). Data presented by McNatty, Cashmore & Young (1972) also raise the possibility that a similar pattern of hormone release may exist in the sheep. However, McNatty et al. (1972) collected samples relatively infrequently and it is hard to define peaks in cortisol concentration. With more  aAdrenal glands  aBlood  aCortisol  aEndocrinology  aMetabolism  aPhysiology  aReproduction  aSheep  aFisiologia  aOvino  aReprodução  aHydrocortisone  tJournal of Endocrinologygv. 79, n. 1, p. 131-132, Oct. 1978.