01671naa a2200325 a 450000100080000000500110000800800410001902400540006010000160011424501820013026000090031252006440032165000380096565000270100365000170103065000160104765000150106365000250107865000120110365000100111565000190112565000120114465000100115665000110116665300260117765300150120365300170121870000150123577300950125015236192023-05-24 1992 bl uuuu u00u1 u #d7 ahttps://doi.org/10.1016/0147-9571(92)90110-D2DOI1 aNAIR, S. P. aA comparative study on the immune response of sheep to foot and mouth disease virus vaccine type Asia-1 prepared with different inactivants and adjuvants.h[electronic resource] c1992 aFoot and mouth disease virus type Asia-1 was inactivated either formaldehyde or binaryethylenimine (BEI). Inactivated vaccines were prepared incorporating aluminium hydroxide gel or mineral oil as an adjuvant. The antibody response to the adult sheep was studied by ELISA and SN test for a period or 6 months. There was no difference in the antibody response between vaccines inactivated with formaldehyde or BEI. Whereas significant difference in the antibody response was observed between gel and oil vaccines. The high titres of antibody stimulated by oil vaccines persisted longer than those of gel vaccines within the period of study. aEnzyme-linked immunosorbent assay aFoot-and-mouth disease aFormaldehyde aGuinea pigs aImmunology aInactivated vaccines aRabbits aSheep aViral vaccines aDoença aOvino aVacina aAdministration dosage aAziridines aFebre aftosa1 aSEN, A. K. tComparative Immunology Microbiology and Infections Diseasegv. 15, n. 2, p. 117-124, 1992.