01397naa a2200265 a 450000100080000000500110000800800410001902400380006010000190009824501500011726000090026752006220027665000200089865000330091865000120095165000170096365000110098065000130099165000170100465300090102165300150103070000150104570000150106077300560107515234472023-05-05 1992 bl uuuu u00u1 u #d7 a10.1016/0093-691x(92)90236-k2DOI1 aPARRISH, J. J. aCurrent concepts of cell-cycle regulation and its relationship to oocyte maturation, fertilization and embryo development.h[electronic resource] c1992 aGenetic and biochemical approaches have contributed to an explosion of literature on cell-cycle control. Regulation of the cell-cycle is controlled by a series of kinases and phosphatases. Key control points are during the G1-S and G2-M transitions. During both transitions, cyclins interact with a specific kinase to allow a cell to pass through that phase. The meiotic maturation of oocytes, fertilization and embryo development are all events influenced by cell-cycle regulation. Understanding cel-cycle control should provide new ways for gamete and ambryo biologists to approach culture and development problems. aEmbryo (animal) aFertilization (reproduction) aOocytes aReproduction aAnimal aEmbrião aReprodução aCdc2 aCell-cycle1 aKIM, C. I.1 aBAE, I. H. tTheriogenologygv. 38, n. 2, p. 277-296, Aug. 1992.