02486naa a2200325 a 450000100080000000500110000800800410001902400310006010000200009124501220011126000090023352015690024265000120181165000330182365000200185665000100187665000150188665000170190165000100191865000190192865000100194765000170195765300190197465300240199370000170201770000170203470000190205170000190207077300710208915233022024-01-02 1992 bl uuuu u00u1 u #d7 a10.1677/joe.0.13402872DOI1 aPHILLIPS, D. J. aBioactive and immunoreactive FSH and immunoreactive inhibin concentrations in the ovine fetus.h[electronic resource] c1992 aAbstract: The bioactive (B) and immunoreactive (I) pituitary contents/concentrations of FSH, together with the plasma concentrations of B-FSH, I-FSH and I-inhibin were determined in ovine fetuses at days 55, 75, 90 and 135 of gestation (day 145 = term). The pituitary contents and concentrations of B-FSH and I-FSH increased in both sexes with gestational age. The female fetuses had significantly (P < 0.01) higher pituitary contents/concentrations of B-FSH and I-FSH than the male fetuses at days 75 and 135. The pituitary B/I ratios of FSH were not significantly different with age or sex. The plasma concentrations of B-FSH remained relatively constant from days 75 to 135, with no significant differences between sexes or with age. In contrast, the plasma concentrations of I-FSH reached a peak at day 90 and then declined towards term in both sexes. At all gestational ages except day 55, the female fetuses had significantly (P < 0.05) higher plasma concentrations of I-FSH than the males. In both sexes, the plasma B/I ratios of FSH were lowest at day 90 and had increased again by day 135, with the male fetuses having significantly (P < 0.05) higher B/I ratios compared with the female group at days 75 and 135 but not at day 90. At all gestational ages, the plasma concentrations of I-inhibin declined throughout gestation in the female fetuses, whereas in the males they reached a nadir at day 75 and then increased towards term. The concentrations of I-inhibin were significantly (P < 0.01) higher in the male fetuses compared with the females aFemales aFollicle-stimulating hormone aGestational age aMales aMetabolism aReproduction aSheep aEndocrinologia aOvino aReprodução aInhibins blood aSex characteristics1 aSMITH, P. R.1 aHEATH, D. A.1 aCONDELL, L. A.1 aMcNATTY, K. P. tThe Journal of Endocrinologygv. 134, n. 2, p. 287-295, Aug. 1992.