01808naa a2200361 a 450000100080000000500110000800800410001902400400006010000200010024501370012026000090025752008060026665000140107265000230108665000130110965000170112265000220113965000140116165000170117565000190119265000170121165000100122865000190123865000150125765000100127265000170128265300170129965300250131665300170134170000200135870000200137877300480139815232602023-05-31       1975    bl uuuu     u00u1 u    #d7 a10.1016/s0090-6980(75)80115-8.2DOI1 aMITCHELL, M. D.  aStimulation by oxytocin of prostaglandin F levels in uterine venous effluent in pregnant and puerperal sheep.h[electronic resource]  c1975  aAbstract: The purpose of this work was to investigate the effect of oxytocin on prostaglandin F (PGF) concentrations in uterine venous effluent. PGF was measured in utero-ovarian venous plasma from three pregnant ewes and in posterior vena caval plasma from two puerperal ewes, during oxytocin administration. Oxytocin caused 4.9 - 5.3-fold increases in PGF concentrations in the pregnant animals, the response increasing towards term. In the puerperal animals oxytocin caused 3.7 - 17.2-fold increases in PGF concentrations with a marked latency in the response. Measurement of uterine activity and progesterone and total unconjugated oestrogen concentrations indicated that neither uterine contractions nor a decreased uterine blood flow accounted for the elevated PGF levels stimulated by oxytocin.  aEstrogens  aMuscle contraction  aOxytocin  aPharmacology  aPostpartum period  aPregnancy  aProgesterone  aProstaglandins  aReproduction  aSheep  aEndocrinologia  aFisiologia  aOvino  aReprodução  aDrug effects  aStimulation dhemical  aTime factors1 aFLINT, A. P. F.1 aTURNBULL, A. C.  tProstaglandinsgv. 9, n. 1, p. 47-56, 1975.