01924naa a2200325 a 450000100080000000500110000800800410001902400310006010000120009124501740010326000090027752010030028665000120128965000100130165000150131165000140132665000170134065000170135765000110137465000120138565000190139765000140141665000150143065000170144565000170146265300210147970000230150070000160152377300590153915227982023-05-18 1976 bl uuuu u00u1 u #d7 a10.1677/joe.0.06803832DOI1 aUMO, I. aParturition in the goatbplasma concentrations of prostaglandin F and steroid hormones and uterine activity during late pregnancy and parturition.h[electronic resource] c1976 aChanges in plasma concentrations of hormones and uterine activity associated with spontaneous parturition in the goat were examined. No change in oestradiol-17β concentration was detected during the experimental period, but oestradiol-17α consistently increased in concentration 3–4 days before parturition. This was followed by an increase in prostaglandin F two days later, while a pre-partum decline in progesterone concentration occurred 18–20 h after the significant increase in prostaglandin F. The onset of uterine contractions coincided with a significant decline in progesterone concentration and a period of continually rising prostaglandin F and oestradiol-17α concentrations. Uterine activity expressed in Montevideo units did not change until 10–8 h before foetal expulsion. These results support the hypothesis that in the goat the elevated prepartum concentration of prostaglandin F brings about luteolysis and a subsequent decline in progesterone concentration. aFemales aGoats aPhysiology aPregnancy aProgesterone aReproduction aUterus aCaprino aEndocrinologia aEstradiol aFisiologia aObstetrícia aReprodução aProstaglandins F1 aFITZPATRICK, R. J.1 aWARD, W. R. tJournal of Endocrinogygv. 68, n. 3, p. 383-389, 1976.