01988naa a2200313 a 450000100080000000500110000800800410001902400320006010000200009224501250011226000090023752011390024665000110138565000100139665000130140665000220141965000130144165000170145465000120147165000190148365000170150265300190151965300100153865300160154865300170156470000190158170000160160077300580161615227332023-04-25 1988 bl uuuu u00u1 u #d7 a10.1530/acta.0.11702602DOI1 aTHORNTON, S. N. aPlasma vasopressin and oxytocin levels in intact goats and in castrated goats given testosterone.h[electronic resource] c1988 aAbstract: Oxytocin, vasopressin, cortisol and testosterone levels in the plasma were measured by radioimmunoassay in intact male goats as well as in prepubertally castrated goats injected daily, for 2 weeks, with oil vehicle and then, for 4 weeks, with testosterone propionate in oil to study the influence of gonadal steroids on posterior pituitary hormones. Packed cell volume, plasma osmolality and sodium concentration were also measured in all blood samples. Plasma levels of oxytocin, vasopressin and cortisol were similar in the intact and oil-injected castrated goats. Testosterone treatment significantly increased plasma levels of oxytocin (P less than 0.01) in castrated goats but the increased levels were similar to those seen in the intact goats at the same time of year. Plasma levels of cortisol and vasopressin were unaffected by testosterone propionate treatment, whereas packed cell volume was significantly decreased (P less than 0.01). Testosterone treatment of castrated male goats appears not to have any action on pituitary hormones and oxytocin increases in the spring in both intact and castrated male goats. aDosage aGoats aOxytocin aRadioimmunoassays aSteroids aTestosterone aCaprino aEndocrinologia aReprodução aHydrocortisone aMacho aOrchiectomy aVasopressins1 aDELANEY, C. E.1 aCHAPMAN, C. tActa Endocrinologicagv. 117, n. 2, p. 260-264, 1988.