01864naa a2200397 a 450000100080000000500110000800800410001902400380006010000180009824501620011626000090027852007510028765000180103865000120105665000100106865000150107865000170109365000170111065000240112765000110115165000120116265000190117465000140119365000150120765000190122265000170124165300170125865300180127565300280129365300210132165300140134265300170135670000150137370000200138877300580140815220842023-05-31       1976    bl uuuu     u00u1 u    #d7 a10.1016/0090-6980(76)90142-82DOI1 aCURRIE, W. B.  aRelease of prostaglandin F, regression of corpora lutea and induction of premature parturition in goats treated with estradiol-17beta.h[electronic resource]  c1976  aAbstract: Premature parturition was induced in five pregnant goats infused intravenously with 4.65-8.4 mg estradiol-17beta but not in one treated with 5.85 mg estradiol-17alpha. A single intramuscular injection of 12 mg estradiol benzoate (8.8 mg estradiol-17beta equivalents) was also effective. These doses were estimated to provide plasma concentrations of estradiol-17beta in the physiological range for animals at sponteneous parturition. Circulating plasma concentrations of progesterone decreased and lactogenesis occurred before all instances of induced parturition but no such changes resulted from infusion of estradiol-17alpha. Placental delivery was normal in all animals but neonates of more than 10 days prematurity were non-viable.  aCorpus luteum  aFemales  aGoats  aMetabolism  aProgesterone  aReproduction  aUterine contraction  aUterus  aCaprino  aEndocrinologia  aEstradiol  aFisiologia  aProstaglandina  aReprodução  aDrug effects  aLabor induced  aPerformance reprodutiva  aProstaglandins F  aPuberdade  aTime factors1 aCOX, R. I.1 aTHORBURN, G. D.  tProstaglandinsgv. 12, n. 6, p. 1093-1103, Dec. 1976.